Evidence map›Paper›PMID 38434718›Full record

ArticleAsian journal of pharmaceutical sciences2024

Synergistic chemotherapy/PTT/oxygen enrichment by multifunctional liposomal polydopamine nanoparticles for rheumatoid arthritis treatment.

Xiaoling Fu, Yutong Song, Xianquan Feng, Zhihong Liu, Wenhao Gao, Hongtao Song, Qian Zhang

Open access · diamondAbstract read
In one paragraph

Article in Asian journal of pharmaceutical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoling FuSchool of Pharmacy, Fujian Medical University, Fuzhou 350108, China.
Yutong SongFirst school of clinical medicine, Nanjing Medical University, Nanjing 211166, China.
Xianquan FengFuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China.
Zhihong LiuFuzong Clinical Medical College of Fujian Medical University, Fuzhou 350025, China.
Wenhao GaoSchool of Pharmacy, Fujian Medical University, Fuzhou 350108, China.
Hongtao SongSchool of Pharmacy, Fujian Medical University, Fuzhou 350108, China.
Qian ZhangSchool of Pharmacy, Fujian Medical University, Fuzhou 350108, China.
Fujian Medical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amultifunctional liposomal polydopamine nanoparticle (MPM@Lipo) was designed in this study, to combine chemotherapy, photothermal therapy (PTT) and oxygen enrichment to clear hyperproliferating inflammatory cells and improve the hypoxic microenvironment for rheumatoid arthritis (RA) treatment. MPM@Lipo significantly scavenged intracellular reactive oxygen species and relieved joint hypoxia, thus contributing to the repolarization of M1 macrophages into M2 phenotype. Furthermore, MPM@Lipo could accumulate at inflammatory joints, inhibit the production of inflammatory factors, and protect cartilage

Indexed as

Oxygen generationPhotothermal therapyPolydopamineRheumatoid arthritisThermosensitive liposomes

Identifiers

PMID38434718
PMCPMC10906176
OpenAlexW4391542648

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.