Evidence map›Paper›PMID 38434620›Full record

ReviewFrontiers in cell and developmental biology2024

The role of long non-coding RNAs and circular RNAs in cervical cancer: modulating miRNA function.

Sama Heidari-Ezzati, Parisa Moeinian, Bahar Ahmadian-Nejad, Faezeh Maghbbouli, Sheida Abbasi, Mahlagha Zahedi, Hamed Afkhami, Alireza Shadab, Nayereh Sajedi

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Role of non-coding RNAs in OOncology letters · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. miR-126: a bridge between cancer and exercise.Cancer cell international · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Sama Heidari-Ezzati *School of Nursing and Midwifery, Bonab University of Medical Sciences, Bonab, Iran.
Parisa Moeinian *Department of Medical Genetics and Molecular Biology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Bahar Ahmadian-NejadSchool of Nursing and Midwifery, Tehran Medical Branch, Islamic Azad University, Tehran, Iran.
Faezeh MaghbbouliTabriz Islamic Azad University of Medical Sciences, Tabriz, Iran.
Sheida AbbasiDepartment of obstetrics and gynecology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mahlagha ZahediDepartment of Pathology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Hamed AfkhamiNervous System Stem Cells Research Center, Semnan University of Medical Sciences, Semnan, Iran.
Alireza ShadabDepartment of Immunology, School of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
Nayereh SajediDepartment of Anatomy, Faculty of Medicine, Qom Medical Sciences, Islamic Azad University, Qom, Iran.
Iranshahr University · IRIran University of Medical Sciences · IRIslamic Azad University of Tabriz · IRQom Islamic Azad University · IRShahid Sadoughi University of Medical Sciences and Health Services · IRStem Cell Technology Research Center · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) is a primary global health concern, ranking as the fourth leading cause of cancer-related death in women. Despite advancements in prognosis, long-term outcomes remained poor. Beyond HPV, cofactors like dietary deficiencies, immunosuppression, hormonal contraceptives, co-infections, and genetic variations are involved in CC progression. The pathogenesis of various diseases, including cancer, has brought to light the critical regulatory roles of microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs). The aberrant expression of these miRNAs, lncRNAs, and circRNAs plays a pivotal role in the initiation and progression of CC. This review provides a comprehensive summary of the recent literature regarding the involvement of lncRNAs and circRNAs in modulating miRNA functions in cervical neoplasia and metastasis. Studies have shown that lncRNAs and circRNAs hold great potential as therapeutic agents and innovative biomarkers in CC. However, more clinical research is needed to advance our understanding of the therapeutic benefits of circRNAs and lncRNAs in CC.

Indexed as

cervical cancercircular RNAslong non-coding RNAsmicroRNAsmiRNA

Identifiers

PMID38434620
PMCPMC10906305
OpenAlexW4391885498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.