Evidence map›Paper›PMID 38434583›Full record

ArticleJournal of inflammation research2024

Serum Homer1 is a Novel Biomarker for Predicting the Clinical Outcomes of Acute Ischemic Stroke Patients.

Weihao Lv, Zhe Ruan, Qianqian Zhang, Yaxuan Wei, Xiuquan Wu, Ya-Nan Dou, Wangshu Chao, Xiaowei Fei, Zhou Fei

Open access · goldAbstract read
In one paragraph

Article in Journal of inflammation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Weihao Lv *Department of Neurosurgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Zhe Ruan *Department of Neurology, Tangdu Hospital, Air Force Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Qianqian Zhang *Department of Respiratory Medicine, Lanzhou University Second Hospital, Lanzhou, 730070, People's Republic of China.
Yaxuan Wei *Department of Neurology, Gansu Province Central Hospital, Lanzhou, 730070, People's Republic of China.
Xiuquan WuDepartment of Neurosurgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Ya-Nan DouDepartment of Neurosurgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Wangshu ChaoDepartment of Neurosurgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Xiaowei FeiDepartment of Neurosurgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Zhou FeiDepartment of Neurosurgery, Xijing Hospital, Air Force Medical University, Xi'an, Shaanxi, 710032, People's Republic of China.
Air Force Medical University · CNXijing Hospital · CNGansu Provincial Hospital · CNLanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We aim to explore the relationship between Homer1 and the outcomes of AIS patients at 3 months. Patients and Methods: This prospective cohort study was conducted from May 2022 to March 2023. In this study, we investigated the association between serum Homer1 levels by enzyme-linked immunosorbent assay at admission and functional outcomes of patients at 3 months after AIS. Results: Overall, 89 AIS patients (48 good outcomes and 41 poor outcomes) and 83 healthy controls were included. The median serum Homer1 level of patients at admission with poor outcomes was significantly higher than that of patients with good outcomes (39.33 vs 33.15, Conclusion: Serum concentrations of Homer1 have a high predictive value for neurobehavioral outcomes after acute ischemic stroke. Higher serum Homer1 levels (>35.07 pg/mL) were positively associated with poor functional outcomes of patients 3 months post-stroke.

Indexed as

acute ischemic strokebiomarkerHomer1outcomes

Identifiers

PMID38434583
PMCPMC10908339
OpenAlexW4392202440

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.