Evidence map›Paper›PMID 38434486›Full record

ArticleJournal of mechanisms and robotics2024

Optimal Concentric Tube Robot Design for Safe Intracerebral Hemorrhage Removal.

Zhefeng Huang, Hussain Alkhars, Anthony Gunderman, Dimitri Sigounas, Kevin Cleary, Yue Chen

Open access · greenAbstract read
In one paragraph

Article in Journal of mechanisms and robotics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zhefeng HuangDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Hussain AlkharsGeorge Washington University School of Medicine, Washington, DC, USA.
Anthony GundermanDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Dimitri SigounasGeorge Washington University School of Medicine, Washington, DC, USA.
Kevin ClearySheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, Washington, DC, USA.
Yue ChenDepartment of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
Georgia Institute of Technology · USGeorge Washington University · USChildren's National · US

Funding

MRI-compatible concentric tube robot for intracerebral hemorrhageR01NS116148 · NINDS · CHILDREN'S RESEARCH INSTITUTE · PI CHEN, YUE, CLEARY, KEVIN R. · 2021 to 2024
$2.3M
NINDS NIH HHS R01 NS116148
6 · The paper itself

Abstract

Purpose: The purpose of this paper is to investigate the geometrical design and path planning of Concentric tube robots (CTR) for intracerebral hemorrhage (ICH) evacuation, with a focus on minimizing the risk of damaging white matter tracts and cerebral arteries. Methods: To achieve our objective, we propose a parametrization method describing a general class of CTR geometric designs. We present mathematical models that describe the CTR design constraints and provide the calculation of a path risk value. We then use a genetic algorithm to determine the optimal tube geometry for targeting within the brain. Results: Our results show that a multi-tube CTR design can significantly reduce the risk of damaging critical brain structures compared to the conventional straight tube design. However, there is no significant relationship between the path risk value and the number and shape of the additional inner curved tubes. Conclusion: Considering the challenges of CTR hardware design, fabrication, and control, we conclude that the most practical geometry for a CTR path in ICH treatment is a straight outer tube followed by a planar curved inner tube. These findings have important implications for the development of safe and effective CTRs for ICH evacuation by enabling dexterous manipulation to minimize damage to critical brain structures.

Indexed as

Concentric tube robot designIntracerebral hemorrhage removalPath planning

Identifiers

PMID38434486
PMCPMC10906783
OpenAlexW4388228983

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.