Evidence map›Paper›PMID 38434323›Full record

ArticleHeliyon2024

Cortical neurons obtained from patient-derived iPSCs with GNAO1 p.G203R variant show altered differentiation and functional properties.

Maria Cristina Benedetti, Tiziano D'andrea, Alessio Colantoni, Denis Silachev, Valeria de Turris, Zaira Boussadia, Valentina A Babenko, Egor A Volovikov, Lilia Belikova, Alexandra N Bogomazova and 10 more

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Pathogenic Gαo Mutants Drive Dominant GPCR Coupling in GNAO1 Encephalopathies.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Novel advanced patient-derivedFrontiers in neurology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 7 institutions in 4 countries.

Maria Cristina BenedettiDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza University of Rome, Rome, Italy.
Tiziano D'andreaDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Rome, Italy.
Alessio ColantoniDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza University of Rome, Rome, Italy.
Denis SilachevSchool of Medicine and Life Sciences, Far Eastern Federal University, 690090, Vladivostok, Russia.
Valeria de TurrisCenter for Life Nano- & Neuro-Science, Fondazione Istituto Italiano di Tecnologia (IIT), Rome, Italy.
Zaira BoussadiaNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
Valentina A BabenkoA.N. Belozersky Research Institute of Physico-Chemical Biology, Moscow State University, 119992, Moscow, Russia.
Egor A VolovikovLopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435, Moscow, Russia.
Lilia BelikovaLopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435, Moscow, Russia.
Alexandra N BogomazovaLopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435, Moscow, Russia.
Rita PepponiNational Center for Drug Research and Evaluation, Istituto Superiore di Sanità, Rome, Italy.
Dosh WhyeHuman Neuron Core, Rosamund Stone Zander Translational Neuroscience Center and F.M. Kirby Neurobiology Department, Boston Children's Hospital, Boston, MA, USA.
Elizabeth D ButtermoreHuman Neuron Core, Rosamund Stone Zander Translational Neuroscience Center and F.M. Kirby Neurobiology Department, Boston Children's Hospital, Boston, MA, USA.
Gian Gaetano TartagliaCenter for Human Technologies (CHT), Istituto Italiano di Tecnologia (IIT), Genova, Italy.
Maria A LagarkovaLopukhin Federal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435, Moscow, Russia.
Vladimir L KatanaevSchool of Medicine and Life Sciences, Far Eastern Federal University, 690090, Vladivostok, Russia.
Ilya MusayevChild's Cure Genetic Research, Fremont, CA, USA.
Simone MartinelliDepartment of Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.
Sergio FucileDepartment of Physiology and Pharmacology "V. Erspamer", Sapienza University of Rome, Rome, Italy.
Alessandro RosaDepartment of Biology and Biotechnologies "Charles Darwin", Sapienza University of Rome, Rome, Italy.
Italian Institute of Technology · ITFederal Medical-Biological Agency · RUIstituto Superiore di Sanità · ITUniversity of Geneva · CHBoston Children's Hospital · USIstituto Neurologico Mediterraneo · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic variants in the

Indexed as

EncephalopathyGNAO1Induced pluripotent stem cellMovement disorderneural rosettewnt

Identifiers

PMID38434323
PMCPMC10907651
OpenAlexW4392005770

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.