Evidence map›Paper›PMID 38434197›Full record

ArticleFrontiers in neurology2024

Case report: Susac syndrome-two ends of the spectrum, single center case reports and review of the literature.

Martina Cviková, Jakub Štefela, Vít Všianský, Michal Dufek, Irena Doležalová, Jan Vinklárek, Roman Herzig, Markéta Zemanová, Vladimír Červeňák, Jaroslav Brichta and 5 more

Registry-linked trialOpen access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06349603 (Integrated Physiotherapy Approach for Susac Syndrome), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06349603 completednot on this map

Integrated Physiotherapy Approach for Susac Syndrome: A Comprehensive Case Study

TypeobservationalSponsorRehabilitation Centre ZivotRan2023 to 2023Enrolled1ConditionsSusac Syndrome
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Susac syndrome - different treatment approaches for one disease (analysis of case series).Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Martina Cviková *Department of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Jakub Štefela *Department of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Vít VšianskýDepartment of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Michal DufekDepartment of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Irena DoležalováDepartment of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Jan VinklárekDepartment of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Roman HerzigDepartment of Neurology, Comprehensive Stroke Center, Charles University Faculty of Medicine and University Hospital, Hradec Králové, Czechia.
Markéta ZemanováDepartment of Ophthalmology and Optometry, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Vladimír ČerveňákDepartment of Medical Imaging, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czechia.
Jaroslav BrichtaDepartment of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
Veronika BárkováDepartment of Clinical Pharmacology, St. Anne's University Hospital, Brno, Czechia.
David KouřilDepartment of Neurology, Blansko Hospital, Blansko, Czechia.
Petr AulickýDepartment of Anesthesiology, Hospital of the Brothers of Charity Brno, Brno, Czechia.
Pavel FilipDepartment of Neurology, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czechia.
Viktor WeissDepartment of Neurology, St. Anne's University Hospital in Brno and Faculty of Medicine at Masaryk University, Brno, Czechia.
St. Anne's University Hospital Brno · CZMasaryk University · CZBlansko Hospital · CZCharles University · CZUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Susac syndrome is a rare and enigmatic complex neurological disorder primarily affecting small blood vessels in the brain, retina, and inner ear. Diagnosing Susac syndrome may be extremely challenging not only due to its rarity, but also due to the variability of its clinical presentation. This paper describes two vastly different cases-one with mild symptoms and good response to therapy, the other with severe, complicated course, relapses and long-term sequelae despite multiple therapeutic interventions. Building upon the available guidelines, we highlight the utility of black blood MRI in this disease and provide a comprehensive review of available clinical experience in clinical presentation, diagnosis and therapy of this disease. Despite its rarity, the awareness of Susac syndrome may be of uttermost importance since it ultimately is a treatable condition. If diagnosed in a timely manner, early intervention can substantially improve the outcomes of our patients.

Indexed as

black blood imagingbranch retinal arterial occlusionhearing lossneuroimmunologystrokeSusac syndromevasculitis

Identifiers

PMID38434197
PMCPMC10904644
OpenAlexW4391893458

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.