Evidence map›Paper›PMID 38434195›Full record

ArticleSovremennye tekhnologii v meditsine2023

Cellular and Molecular Mechanisms of Toxic Liver Fibrosis in Rats Depending on the Stages of Its Development.

E I Lebedeva, A T Shchastniy, A S Babenka

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Sovremennye tekhnologii v meditsine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

E I LebedevaAssociate Professor, Department of Histology, Cytology and Embryology; Vitebsk State Order of Peoples' Friendship Medical University, 27 Frunze Avenue, Vitebsk, 210009, the Republic of Belarus.
A T ShchastniyProfessor, Head of the Department of Hospital Surgery with the Course of the Fetoplacental Complex and Placental Complex; Vitebsk State Order of Peoples' Friendship Medical University, 27 Frunze Avenue, Vitebsk, 210009, the Republic of Belarus.
A S BabenkaAssociate Professor, Department of Bioorganic Chemistry; Belarusian State Medical University, 83 Dzerzhinsky Avenue, Minsk, 220116, the Republic of Belarus.
Vitebsk State Medical University · BYBelarusian State Medical University · BY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Materials and Methods: Liver fibrogenesis in male Wistar rats was induced with the thioacetamide solution by introducing into the stomach with a probe at a dose of 200 mg/kg of animal body weight 2 times per week. The process dynamics was studied at 5 time points (control, week 3, week 5, week 7, and week 9). The mRNA levels of Results: Two simultaneously existing morphologically heterogeneous populations of myofibroblasts expressing different types of markers (FAP, α-SMA) were identified in rat liver. Prior to the onset of transformation of fibrosis into cirrhosis (F1-F4, weeks 3-7), FAP Conclusion: It was established that the stages of toxic fibrosis had morphological and molecular genetic features. The FAP

Indexed as

Endothelial CellsMatrix Metalloproteinase 9AnimalsLiver CirrhosisMaleRatsRats, WistarRNA, MessengerMatrix Metalloproteinase 9RNA, MessengerimmunohistochemistryIshak’s scalemRNA expressionrat liver fibrogenesistoxic fibrosis

Identifiers

PMID38434195
PMCPMC10902903
OpenAlexW4386292360

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.