Evidence map›Paper›PMID 38433995›Full record

ArticleNeurobiology of stress2024

Sex-specific threat responding and neuronal engagement in carbon dioxide associated fear and extinction: Noradrenergic involvement in female mice.

Rebecca Ahlbrand, Allison Wilson, Patrick Woller, Yuv Sachdeva, Jayden Lai, Nikki Davis, James Wiggins, Renu Sah

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of stress, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Sex differences in responses to panicogen COFrontiers in cellular neuroscience · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Rebecca AhlbrandDepartment of Pharmacology and Systems Physiology, University of Cincinnati, USA.
Allison WilsonNeuroscience Undergraduate Program, University of Cincinnati, USA.
Patrick WollerNeuroscience Graduate Program, University of Cincinnati, USA.
Yuv SachdevaDepartment of Pharmacology and Systems Physiology, University of Cincinnati, USA.
Jayden LaiDepartment of Pharmacology and Systems Physiology, University of Cincinnati, USA.
Nikki DavisNeuroscience Undergraduate Program, University of Cincinnati, USA.
James WigginsNeuroscience Undergraduate Program, University of Cincinnati, USA.
Renu SahDepartment of Pharmacology and Systems Physiology, University of Cincinnati, USA.
University of Cincinnati · US

Funding

Neurovascular signaling and associated forebrain circuits in PTSDI01BX001075 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI SAH, RENU · 2011 to 2025
–
BLRD VA I01 BX001075
6 · The paper itself

Abstract

Difficulty in appropriately responding to threats is a key feature of psychiatric disorders, especially fear-related conditions such as panic disorder (PD) and posttraumatic stress disorder (PTSD). Most prior work on threat and fear regulation involves exposure to external threatful cues. However, fear can also be triggered by aversive, within-the-body, sensations. This interoceptive signaling of fear is highly relevant to PD and PTSD but is not well understood, especially in the context of sex. Using female and male mice, the current study investigated fear-associated spontaneous and conditioned behaviors to carbon dioxide (CO

Indexed as

CO2ExtinctionFearNoradrenergicPanicPTSDSex differences

Identifiers

PMID38433995
PMCPMC10907837
OpenAlexW4391972909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.