Evidence map›Paper›PMID 38433986›Full record

ArticleNeuroscience informatics2024

A curious case of retrogenesis in language: Automated analysis of language patterns observed in dementia patients and young children.

Changye Li, Jacob Solinsky, Trevor Cohen, Serguei Pakhomov

Abstract read
In one paragraph

Article in Neuroscience informatics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Changye LiInstitute of Health Informatics, University of Minnesota, Minneapolis, 55455, MN, USA.
Jacob SolinskyCollege of Pharmacy, University of Minnesota, Minneapolis, 55455, MN, USA.
Trevor CohenDivision of Biomedical Informatics and Medical Education, University of Washington, Seattle, 98195, WA, USA.
Serguei PakhomovCollege of Pharmacy, University of Minnesota, Minneapolis, 55455, MN, USA.

Funding

Computerized assessment of linguistic indicators of lucidity in Alzheimer's Disease dementiaR21AG069792 · NIA · UNIVERSITY OF MINNESOTA · PI MICHALOWSKI, MARTIN, PAKHOMOV, SERGUEI VS · 2020 to 2021
$671k
NIA NIH HHS R21 AG069792
6 · The paper itself

Abstract

Introduction: While linguistic retrogenesis has been extensively investigated in the neuroscientific and behavioral literature, there has been little work on retrogenesis using computerized approaches to language analysis. Methods: We bridge this gap by introducing a method based on comparing output of a pre-trained neural language model (NLM) with an artificially degraded version of itself to examine the transcripts of speech produced by seniors with and without dementia and healthy children during spontaneous language tasks. We compare a range of linguistic characteristics including language model perplexity, syntactic complexity, lexical frequency and part-of-speech use across these groups. Results: Our results indicate that healthy seniors and children older than 8 years share similar linguistic characteristics, as do dementia patients and children who are younger than 8 years. Discussion: Our study aligns with the growing evidence that language deterioration in dementia mirrors language acquisition in development using computational linguistic methods based on NLMs. This insight underscores the importance of further research to refine its application in guiding developmentally appropriate patient care, particularly in early stages.

Indexed as

Alzheimer’s diseaseComputational linguisticsNatural language processingRetrogenesis

Identifiers

PMID38433986
PMCPMC10907010

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.