Evidence map›Paper›PMID 38433949›Full record

ArticleClinical and translational radiation oncology2024

The role of online MR-guided multi-fraction stereotactic ablative radiotherapy in lung tumours.

Svenja Hering, Alexander Nieto, Sebastian Marschner, Jan Hofmaier, Nina-Sophie Schmidt-Hegemann, Vanessa da Silva Mendes, Guillaume Landry, Maximilian Niyazi, Farkhad Manapov, Claus Belka and 2 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Detection and localization of radiation-induced pneumonitis usingPhysics and imaging in radiation oncology · 2025
    Article
  4. Article
  5. MR-guided online adaptive stereotactic body radiotherapy (MRgSBRT) of primary lung tumors and lung oligometastases.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Svenja HeringDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Alexander NietoDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Sebastian MarschnerDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Jan HofmaierDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Nina-Sophie Schmidt-HegemannDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Vanessa da Silva MendesDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Guillaume LandryDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Maximilian NiyaziDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Farkhad ManapovDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Claus BelkaDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
Chukwuka EzeDepartment of Radiation Oncology, LMU University Hospital, LMU Munich, Munich, Germany.
LMU Klinikum · DEGerman Cancer Research Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of this prospective observational study was to evaluate the dosimetry benefits, changes in pulmonary function, and clinical outcome of online adaptive MR-guided SBRT. Methods: From 11/2020-07/2022, 45 consecutive patients with 59 lesions underwent multi-fraction SBRT (3-8 fractions) at our institution. Patients were eligible if they had biopsy-proven NSCLC or lung cancer/metastases diagnosed via clinical imaging. Endpoints were local control (LC) and overall survival (OS). We evaluated PTV/GTV dose coverage, organs at risk exposure, and changes in pulmonary function (PF). Acute toxicity was classified per the National Cancer Institute-Common Terminology Criteria for Adverse Events version 5.0. Results: The median PTV was 14.4 cm Conclusions: Online adaptive MR-guided SBRT is an effective, safe and generally well tolerated treatment option for lung tumours achieving encouraging local control rates with significantly improved target volume coverage.

Indexed as

Lung cancerMR-guided radiotherapyMR-guided SABRMR-guided SBRTMR-Linac, SBRT, SABR, lung metastasesRadiation oncology

Identifiers

PMID38433949
PMCPMC10909605
OpenAlexW4391345424

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.