Evidence map›Paper›PMID 38433863›Full record

ReviewFrontiers in cellular neuroscience2024

A helping hand: roles for accessory cells in the sense of touch across species.

David R Logan, Jesse Hall, Laura Bianchi

Abstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

David R LoganDepartment of Physiology and Biophysics, University of Miami, Miami, FL, United States.
Jesse HallDepartment of Physiology and Biophysics, University of Miami, Miami, FL, United States.
Laura BianchiDepartment of Physiology and Biophysics, University of Miami, Miami, FL, United States.

Funding

Glial ion channels in glia/neurons interactions.R01NS105616 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Laura Bianchi · 2018 to 2026
$3.2M
Molecular Genetics of Synaptic PlasticityR01NS106951 · NINDS · VANDERBILT UNIVERSITY · PI BIANCHI, LAURA, MILLER, DAVID M · 2018 to 2022
$2.2M
Glial KCNQ channels.R01NS127146 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Laura Bianchi · 2022 to 2026
$1.9M
Glia in Touch SensationR01NS070969 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BIANCHI, LAURA · 2011 to 2015
$1.6M
NINDS NIH HHS R01 NS070969NINDS NIH HHS R01 NS105616NINDS NIH HHS R01 NS106951NINDS NIH HHS R01 NS127146
6 · The paper itself

Abstract

During touch, mechanical forces are converted into electrochemical signals by tactile organs made of neurons, accessory cells, and their shared extracellular spaces. Accessory cells, including Merkel cells, keratinocytes, lamellar cells, and glia, play an important role in the sensation of touch. In some cases, these cells are intrinsically mechanosensitive; however, other roles include the release of chemical messengers, the chemical modification of spaces that are shared with neurons, and the tuning of neural sensitivity by direct physical contact. Despite great progress in the last decade, the precise roles of these cells in the sense of touch remains unclear. Here we review the known and hypothesized contributions of several accessory cells to touch by incorporating research from multiple organisms including

Indexed as

accessory cellsC. elegansDrosophilagliamechanotransductiontouch

Identifiers

PMID38433863
PMCPMC10904576

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.