Evidence map›Paper›PMID 38433741›Full record

ArticleTopics in spinal cord injury rehabilitation2024

Association of Calcium and Vitamin D Supplements with Fractures in Persons with a Traumatic SCI.

Brian Le, Hongyan Nathan Xu, Frances M Weaver, Zhiping Jenny Huo, Ryan Avidano, Piper Hurlburt, Sarah Morgan, Laura Carbone

Open access · greenAbstract read
In one paragraph

Article in Topics in spinal cord injury rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Brian LeCharlie Norwood Veterans Administration Medical Center, Augusta, Georgia.
Hongyan Nathan XuDivision of Biostatistics & Data Science, Department of Population Health Sciences, Medical College of Georgia, Augusta University, Augusta, Georgia.
Frances M WeaverCenter of Innovation for Complex Chronic Healthcare (CINCCH), Health Services Research & Development, Department of Veterans Affairs, Hines VA Hospital, Hines, Illinois.
Zhiping Jenny HuoCenter of Innovation for Complex Chronic Healthcare (CINCCH), Health Services Research & Development, Department of Veterans Affairs, Hines VA Hospital, Hines, Illinois.
Ryan AvidanoDepartment of Medicine, Division of Rheumatology, Medical College of Georgia at Augusta University, Augusta, Georgia.
Piper HurlburtDepartment of Medicine, Division of Rheumatology, Medical College of Georgia at Augusta University, Augusta, Georgia.
Sarah MorganDivision of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, Alabama.
Laura CarboneCharlie Norwood Veterans Administration Medical Center, Augusta, Georgia.
Augusta University · USCharlie Norwood VA Medical Center · USEdward Hines, Jr. VA Hospital · USHealth Services Research & Development · USUniversity of Alabama at Birmingham · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Osteoporotic fractures occur in almost half of patients with a spinal cord injury (SCI) and are associated with significant morbidity and excess mortality. Paralyzed Veterans Administration (PVA) guidelines suggest that adequate calcium and vitamin D intake is important for skeletal health, however, the association of these supplements with osteoporotic fracture risk is unclear. Objectives: To determine the association of filled prescriptions for calcium and vitamin D with fracture risk in Veterans with an SCI. Methods: The 5897 persons with a traumatic SCI of at least 2 years' duration (96% male; 4% female) included in the VSSC SCI/D Registry in FY2014 were followed from FY2014 to FY2020 for incident upper and lower extremity fractures. Filled daily prescriptions for calcium or vitamin D supplements for ≥6 months with an adherence ≥80% were examined. Results: Filled prescriptions for calcium (hazard ratio [HR] 0.65; 95% CI, 0.54-0.78) and vitamin D (HR 0.33; 95% CI, 0.29-0.38) supplements were associated with a significantly decreased risk for incident fractures. Conclusion: Calcium and vitamin D supplements are associated with decreased risk of fracture, supporting PVA guidelines that calcium and vitamin D intake are important for skeletal health in persons with an SCI.

Indexed as

Fractures, BoneSpinal Cord InjuriesCalciumDietary SupplementsFemaleHumansMaleVitamin DCalciumVitamin Dcalcium and vitamin D supplementsfracturesspinal cord injury

Identifiers

PMID38433741
PMCPMC10906370
OpenAlexW4391887895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.