Evidence map›Paper›PMID 38433527›Full record

ArticleCancer science2024

Region-specific DNA hydroxymethylation along the malignant progression of IDH-mutant gliomas.

Taijun Hana, Akitake Mukasa, Masashi Nomura, Genta Nagae, Shogo Yamamoto, Kenji Tatsuno, Hiroki Ueda, Shiro Fukuda, Takayoshi Umeda, Shota Tanaka and 10 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 2 countries.

Taijun HanaDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-7649-3305
Akitake MukasaDepartment of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.ORCID https://orcid.org/0000-0001-7776-9086
Masashi NomuraDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-6095-7849
Genta NagaeGenome Science & Medicine Laboratory, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-2929-7990
Shogo YamamotoGenome Science & Medicine Laboratory, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-5564-2567
Kenji TatsunoGenome Science & Medicine Laboratory, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.
Hiroki UedaGenome Science & Medicine Laboratory, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.
Shiro FukudaGenome Science & Medicine Laboratory, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-0065-662X
Takayoshi UmedaGenome Science & Medicine Laboratory, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.
Shota TanakaDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Takahide NejoDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-9191-8823
Yosuke KitagawaDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0002-1903-1283
Erika YamazawaDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Satoshi TakahashiDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Tsukasa KoikeDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Yoshihiro KushiharaDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hirokazu TakamiDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.ORCID https://orcid.org/0000-0001-9742-7462
Shunsaku TakayanagiDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Hiroyuki AburataniGenome Science & Medicine Laboratory, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.
Nobuhito SaitoDepartment of Neurosurgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Tokyo University of Science · JPUniversity of Tokyo Hospital · JPKumamoto University · JPUniversity of California, San Francisco · US

Funding

Japan Society for the Promotion of Science 17H04300Japan Society for the Promotion of Science 20H03792
6 · The paper itself

Abstract

The majority of low-grade isocitrate dehydrogenase-mutant (IDH

Indexed as

Brain NeoplasmsDisease ProgressionDNA MethylationGene Expression Regulation, NeoplasticGliomaIsocitrate DehydrogenaseKruppel-Like Factor 4Mutation5-MethylcytosineAdultAstrocytomaCpG IslandsFemaleHumansMaleMiddle Aged5-MethylcytosineIsocitrate DehydrogenaseKruppel-Like Factor 45‐hydroxymethyl cytosine (5hmC)gliomahydroxymethylationisocitrate dehydrogenase (IDH)malignant progression

Identifiers

PMID38433527
PMCPMC11093199
OpenAlexW4392371538

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.