Evidence map›Paper›PMID 38433376›Full record

ArticleAmerican journal of hematology2024

Leg ulcers are indicators of systemic dysfunction in individuals with sickle cell disease.

Tiffany A Jackson, Ashley J Buscetta, Hasmin C Ramirez, Vence L Bonham, Caterina P Minniti

Abstract readLetter
In one paragraph

Article in American journal of hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tiffany A JacksonHealth Disparities Unit, Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.ORCID 0000-0002-8645-9570
Ashley J BuscettaHealth Disparities Unit, Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.
Hasmin C RamirezHealth Disparities Unit, Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.
Vence L BonhamHealth Disparities Unit, Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, Maryland, USA.
Caterina P MinnitiDepartment of Medicine, Einstein College of Medicine, Bronx, New York, USA.ORCID 0000-0002-7059-2959

Funding

Einstein-Montefiore Clinical and Translational Science Award HubUM1TR004400 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Jessica Kahn, Mimi Y Kim · 2023 to 2026
$17.3M
Insights into Sickle Cell Trait and Sickle Cell DiseaseZIAHG200394 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BONHAM, VENCE L · 2014 to 2025
$3.8M
Intramural NIH HHS ZIA HG200394NCATS NIH HHS UM1 TR004400NHGRI NIH HHS 1ZIAHG200394-01
6 · The paper itself

Abstract

Leg ulcers in individuals living with Sickle Cell Disease are evidence of systemic dysfunction. Data from a U.S. study link leg ulcers to wider pulse pressure and markers of chronic hemolysis, inflammation, renal, and liver dysfunction.

Indexed as

Anemia, Sickle CellLeg UlcerBlood PressureHemolysisHumansInflammation

Identifiers

PMID38433376
PMCPMC10979399

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.