Evidence map›Paper›PMID 38433196›Full record

ArticleWorld journal of surgical oncology2024

Involvement of CX3CR1

Seiji Natsuki, Mami Yoshii, Hiroaki Tanaka, Takuya Mori, Sota Deguchi, Yuichiro Miki, Tatsuro Tamura, Takahiro Toyokawa, Shigeru Lee, Kiyoshi Maeda

Open access · goldAbstract read
In one paragraph

Article in World journal of surgical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Seiji NatsukiDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Mami YoshiiDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan. t21137i@omu.ac.jp.
Hiroaki TanakaDepartment of Surgery, Fuchu Hospital, Osaka, Japan.
Takuya MoriDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Sota DeguchiDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Yuichiro MikiDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Tatsuro TamuraDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Takahiro ToyokawaDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Shigeru LeeDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Kiyoshi MaedaDepartment of Gastroenterological Surgery, Osaka City University Graduate School of Medicine, Asahi-machi 1-4-3, Abeno-ku, Osaka, Japan.
Osaka City University · JPFuchu Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGastric cancer is primarily treated by surgery; however, little is known about the changes in the intraperitoneal immune environment and the prognostic impact of surgery. Surgical stress and cancer-associated inflammation cause immune cells to mobilize into the abdominal cavity via numerous cytokines. One such cytokine, CX3CR1, has various immune-related functions that remain to be fully explained. We characterized the intraperitoneal immune environment by investigating CX3CR1

methodsLavage fluid samples were obtained from a total of 41 patients who underwent gastrectomy. The relative expression of various genes was analyzed using quantitative real-time PCR. The association of each gene expression with clinicopathological features and surgical outcomes was examined. The fraction of CX3CR1

resultsCX3CR1

conclusionsOur results suggest that CX3CR1

Indexed as

Abdominal CavityStomach NeoplasmsCX3C Chemokine Receptor 1CytokinesGastrectomyHumansImmunosuppressive AgentsInflammationCX3C Chemokine Receptor 1CX3CR1 protein, humanCytokinesImmunosuppressive AgentsCX3CR1Fractalkine receptorGastric cancerIntraperitoneal lavage fluidMyeloid-derived suppressor cellProgrammed death 1Tumor-associated macrophage

Identifiers

PMID38433196
PMCPMC10910822
OpenAlexW4392372381

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.