ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024
Outcomes of parenteral nutrition in patients with advanced cancer and malignant bowel obstruction.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 4 citations in OpenAlex.
- The multidimensional impact of malnutrition in incurable cancer.Current opinion in supportive and palliative care · 2026Review
- Non-surgical management of malignant bowel obstruction: strategies and outcomes in inoperable patients.Journal of gastrointestinal oncology · 2026Article
- Effects of Dietary Interventions on Nutritional Status in Patients with Gastrointestinal Cancers: A Systematic Review.Biomedicines · 2026Review
- Outcomes following diagnostic laparoscopy in patients with peritoneal carcinomatosis deemed ineligible for cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) due to disease burden.Surgical oncology insight · 2025Article
- Letter to the editor to "Outcomes of parenteral nutrition in patients with advanced cancer and malignant bowel obstruction".Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
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Authors and funding
14 authors at 1 institution in 1 country.
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Abstract
backgroundMalignant bowel obstruction (MBO) affects 3% to 15% of all cancer patients. In patients with advanced cancer and inoperable MBO, the average survival varies between four to nine weeks. Parenteral nutrition (PN) may improve survival in specific patient populations with malignant bowel obstruction.
aimsThis retrospective, single-center cohort study aimed to review individual patient outcomes on PN in the setting of advanced cancer with a diagnosis of MBO and identify clinical and laboratory markers predictive of short- and long-term survival to further highlight patients that would benefit from PN in the setting of an inoperable MBO.
resultsIn a retrospective analysis of 68 patients receiving PN for inoperable MBO, the median survival was 142 (IQR: 63.3-239.5) days. Patients experienced a median number of two hospital readmissions (range: 0-10) and spent a median of 29 days (range: 0-105) in the hospital after starting PN. Eighteen (26.5%) patients developed a catheter-related bloodstream infection (CRBSI). A diagnosis of appendiceal cancer was identified as a predictive marker of improved survival (HR: 0.53, 95% CI: 0.29-0.92, p = 0.023).
conclusionsThe use of PN in the context of end-of-life cancer care is a practice that necessitates improvement. Recognizing the outcomes and patient experiences of PN utilization is essential to physicians and patients.
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