Evidence map›Paper›PMID 38433152›Full record

ArticleAnnals of biomedical engineering2024

The Effect of Simulated Obstructive Apneas on Mechanical Characteristics of Lower Airways in Individuals with Asthma.

Nasim Montazeri Ghahjaverestan, Shaghayegh Chavoshian, Xiaoshu Cao, T Douglas Bradley, Susan M Tarlo, Matthew Stanbrook, Kenneth R Chapman, Azadeh Yadollahi

Abstract read
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In one paragraph

Article in Annals of biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nasim Montazeri GhahjaverestanKITE, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada.
Shaghayegh ChavoshianKITE, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada.
Xiaoshu CaoKITE, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada.
T Douglas BradleyKITE, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada.
Susan M TarloDepartment of Medicine, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
Matthew StanbrookToronto Western Hospital, University Health Network, Toronto, ON, Canada.
Kenneth R ChapmanDepartment of Medicine, University of Toronto, Toronto, ON, Canada.
Azadeh YadollahiKITE, University Health Network Toronto Rehabilitation Institute, Toronto, ON, Canada. azadeh.yadollahi@uhn.ca.
University of Toronto · CAUniversity Health Network · CAToronto General Hospital · CAToronto Western Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased negative intrathoracic pressure that occurs during pharyngeal obstruction can increase thoracic fluid volume that may contribute to lower airway narrowing in individuals with obstructive sleep apnea (OSA) and asthma. Our previous study showed that fluid accumulation in the thorax induced by simulated OSA can increase total respiratory resistance. However, the effect of fluid shift on lower airway narrowing has not been investigated. To examine the effect of fluid accumulation in the thorax on the resistance of the lower airway. Non-asthma participants and individuals with (un)controlled asthma were recruited and underwent a single-day experiment. A catheter with six pressure sensors was inserted through the nose to continuously measure pressure at different sites of the airway, while a pneumotachograph was attached to a mouthpiece to record airflow. To simulate obstructive apneas, participants performed 25 Mueller maneuvers (MMs) while lying supine. Using the recordings of pressure sensor and airflow, total respiratory (R

Indexed as

AsthmaSleep Apnea, ObstructiveAdultAirway ResistanceFemaleHumansMaleMiddle AgedModels, BiologicalAsthmaNegative intrathoracic pressureObstructive sleep apneaThoracic fluid volume

Identifiers

PMID38433152
OpenAlexW4392343380

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.