Evidence map›Paper›PMID 38432882›Full record

ReviewZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2023

Research progress in the correlation between SREBP/PCSK9 pathway and lipid metabolism disorders induced by antipsychotics.

Jiashu Ma, Yunshao Zheng, Fengxia Sun, Yunli Fan, Yunming Fan, Xianbiao Su, Zhongbao Wang, Ning Weng, Ranran Li

Open access · greenAbstract readReview
In one paragraph

Review in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jiashu MaSchool of Mental Health, Jining Medical University, Jining Shandong 272067. 2224020908@qq.com.
Yunshao ZhengDepartment of Psychiatry, Shandong Mental Health Center, Jinan 250014.
Fengxia SunDepartment of Psychiatry, Shandong Mental Health Center, Jinan 250014.
Yunli FanDepartment of Psychiatry, Shandong Mental Health Center, Jinan 250014.
Yunming FanDepartment of Psychiatry, Shandong Mental Health Center, Jinan 250014.
Xianbiao SuDepartment of Psychiatry, Shandong Mental Health Center, Jinan 250014.
Zhongbao WangDepartment of Psychiatry, Shandong Daizhuang Hospital, Jining Shandong 272051, China.
Ning WengDepartment of Psychiatry, Shandong Mental Health Center, Jinan 250014.
Ranran LiDepartment of Psychiatry, Shandong Mental Health Center, Jinan 250014. dtlrr113@126.com.
Shandong Mental Health Center · CNJining Medical University · CNJining Traditional Chinese Medicine Hospital · CN

Funding

the National Natural Science Foundation 82101580the Traditional Chinese Medicine Science and Technology Development Project of Shandong Province 2019-0528
6 · The paper itself

Abstract

Antipsychotic medications are commonly used to treat schizophrenia, but they can have negative effects on lipid metabolism, leading to an increased risk of cardiovascular diseases, reduced life expectancy, and difficulties with treatment adherence. The specific mechanisms by which antipsychotics disrupt lipid metabolism are not well understood. Sterol regulatory element-binding proteins (SREBPs) are important transcriptional factors that regulate lipid metabolism. Proprotein convertase subtilisin/kexin type 9 (

Indexed as

Antipsychotic AgentsLipid Metabolism DisordersHumansLipid MetabolismProprotein Convertase 9Sterol Regulatory Element Binding Protein 1Antipsychotic AgentsPCSK9 protein, humanProprotein Convertase 9Sterol Regulatory Element Binding Protein 1abnormal lipid metabolismantipsychoticsproprotein convertase subtilisin/kexin type 9sterol regulatory element-binding proteins

Identifiers

PMID38432882
PMCPMC10929898
OpenAlexW4394764096

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.