Evidence map›Paper›PMID 38431591›Full record

Trial reportJournal of neuroengineering and rehabilitation2024

Effects of the powerball® system on muscle strength, coordination, fatigue, functionality and quality of life in people with multiple sclerosis. A randomized clinical trial.

Aitor Blázquez-Fernández, Gemma López-Hazas-Jiménez, Diego Fernández-Vázquez, Víctor Navarro-López, Pilar Fernández-González, Selena Marcos-Antón, Francisco Molina-Rueda, Roberto Cano-de-la-Cuerda

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of neuroengineering and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07244133 (Comparative Effects Of Powerball Using Static and Dynamic Surface on Upper Limb Endurance and Coordination in Children With Down Syndrome), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07244133 narecruitingnot on this mapstarted 2025, after this paper: background citation

Comparative Effects Of Powerball Using Static and Dynamic Surface on Upper Limb Endurance and Coordination in Children With Down Syndrome

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2026Enrolled28ConditionsDown SyndromeArmsPower ball with static surface, Powerball with dynamic surface
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. The Impact of Upper Extremity Rehabilitation on Fatigue in Individuals With Multiple Sclerosis: A Systematic Review.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026
    Pooled it
  2. Trial
  3. Article
  4. Does kinesio taping affect balance in individuals with multiple sclerosis?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aitor Blázquez-FernándezMultiple Sclerosis Association of Leganés. Leganés, Madrid, Spain.
Gemma López-Hazas-JiménezMultiple Sclerosis Association of Fuenlabrada. Fuenlabrada, Madrid, Spain.
Diego Fernández-VázquezDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Faculty of Health Sciences, Rey Juan Carlos University, Alcorcón, Madrid, Spain. diego.fernandez@urjc.es.
Víctor Navarro-LópezDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Faculty of Health Sciences, Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Pilar Fernández-GonzálezDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Faculty of Health Sciences, Rey Juan Carlos University, Alcorcón, Madrid, Spain. pilar.fernandez@urjc.es.
Selena Marcos-AntónMultiple Sclerosis Association of Leganés. Leganés, Madrid, Spain.
Francisco Molina-RuedaDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Faculty of Health Sciences, Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Roberto Cano-de-la-CuerdaDepartment of Physical Therapy, Occupational Therapy, Physical Medicine and Rehabilitation, Faculty of Health Sciences, Rey Juan Carlos University, Alcorcón, Madrid, Spain.
Universidad Rey Juan Carlos · ESHospital Universitario de Fuenlabrada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAlthough clinical and functional impairments in the lower limbs have been extensively studied in patients with MS, the upper limb (UL) are also frequently affected. Clinical impairment of the UL in patients with MS is very common with muscle strength and hand dexterity as critical factors in maintaining functional activities that are the basis for independence and quality of life in people with MS.

objectiveTo investigate the effects of a training protocol using the Powerball® system in combination with conventional physiotherapy on muscle strength, coordination, fatigue, functionality, and quality of life in persons with MS over an 8-week period. MATERIALS AND

methodsA double-blind randomized controlled trial was conducted. The control group received conventional treatment, while the experimental group received additional UL training using the Powerball® system. Both groups received the same number of sessions and weeks of intervention. The following outcome measures were used: isometric grip and pinch strength, Box and Block Test (BBT), Nine Hole Peg Test (NHPT), Abilhand scale, Fatigue Severity Scale (FSS), Multiple Sclerosis Impact Scale (MSIS-29), and Likert satisfaction questionnaire for the experimental group. All measures were administered at baseline, after the treatment, and during a 3-week follow-up period.

results25 patients completed the study (12 in the experimental and 13 in the control group). The experimental group showed significant improvements in coordination and manual dexterity of the more affected UL as measured by the BBT comparing pre- to post-treatment (p = 0.048) and pre-treatment to follow-up (p = 0.001), and on the less affected UP comparing pre-treatment to follow-up (p < 0.001) and post-treatment to follow-up (p = 0.034). The Likert-type satisfaction questionnaire obtained a mean score of 89.10 (± 8.54) out of 100 points.

conclusionsUpper limb treatment protocol using the Powerball® system, in combination with conventional physiotherapy for 8 weeks resulted in significant improvements in the intra-group analysis for UL coordination and manual dexterity in favor of the experimental group. The experimental group showed excellent satisfaction to the treatment.

Indexed as

Multiple SclerosisFatigueHand StrengthHumansMuscle StrengthQuality of LifeUpper ExtremityCoordinationFatigueFunctionalityMultiple sclerosisMuscular strengthPowerball systemQuality of lifeRehabilitation

Identifiers

PMID38431591
PMCPMC10908022
OpenAlexW4392348352

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.