ArticleBMC public health2024
Association of volatile organic compound exposure with metabolic syndrome and its components: a nationwide cross-sectional study.
Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Association of environmental xylene exposure with diabetic kidney disease: a cross-sectional analysis and multi-omics evaluation of immune microenvironment mechanisms.Renal failure · 2026Article
- Respirator-integrated continuous gas sampling for broadband optical spectroscopy.Scientific reports · 2026Article
- Urinary Volatile Organic Compound Metabolites Are Associated With MASLD/MASH in Humans and Induce Steatosis in Liver Organoids.Liver international : official journal of the International Association for the Study of the Liver · 2026Article
- Association of volatile organic compounds with serum lactate dehydrogenase levels in the general adults.International archives of occupational and environmental health · 2026Article
- [Exposures to volatile organic compounds are positively correlated with risks of metabolic dysfunction-associated steatotic liver disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026Article
- Article
- Clustering environmental pollutants associated with increased risk of metabolic disease: a hierarchical analysis.Health information science and systems · 2025Article
- Cumulative environmental exposures and metabolic syndrome: A study of heavy metals and volatile organic compounds.Ecotoxicology and environmental safety · 2025Article
- Volatile organic compound exposure is associated with hyperuricemia in the general population: an analysis of 6878 adults from the NHANES.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Association Between Volatile Organic Compounds and Circadian Syndrome Among Pre- and Postmenopausal Women.Toxics · 2025Article
- Association between exposure to volatile organic compounds and atherogenic index of plasma in NHANES 2011-2018.Scientific reports · 2025Article
- Article
- Inflammatory markers partially mediate the association between volatile organic compounds exposure and hyperlipidemia: a nationally representative cross-sectional study from NHANES.Frontiers in public health · 2025Article
- Volatile organic compounds exposure associated with frailty in United States adults from NHANES 2011-2018.Frontiers in public health · 2025Article
- Independent and combined associations of VOCs exposure and MetS in theFrontiers in public health · 2025Article
- Association between urinary volatile organic compounds metabolites and rheumatoid arthritis among the adults from NHANES 2011-2018.Scientific reports · 2024Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundMetabolic syndrome (MetS) is a health issue consisting of multiple metabolic abnormalities. The impact of exposure to volatile organic compounds (VOCs) on MetS and its components remains uncertain. This study aimed to assess the associations of individual urinary metabolites of VOC (mVOCs) and mVOC mixtures with MetS and its components among the general adult population in the United States.
methodsA total of 5345 participants with eligible data were filtered from the 2011-2020 cycles of the National Health and Nutrition Examination Survey. Multivariate logistic regression models were applied to assess the associations of individual mVOCs with MetS and its components. The least absolute shrinkage and selection operator (LASSO) regression models were constructed to identify more relevant mVOCs. The weight quantile sum regression model was applied to further explore the links between mVOC co-exposure and MetS and its components.
resultsThe results indicated positive associations between multiple mVOCs and MetS, including CEMA, DHBMA, and HMPMA. CEMA was found to be positively correlated with all components of MetS. HMPMA was associated with elevated triglyceride (TG), reduced high-density lipoprotein, and fasting blood glucose (FBG) impairment; 3HPMA was associated with an elevated risk of high TG and FBG impairment; and DHBMA had positive associations with elevated TG and high blood pressure. The co-exposure of LASSO-selected mVOCs was associated with an increased risk of elevated TG, high blood pressure, and FBG impairment.
conclusionPositive associations of certain individual urinary mVOCs and mVOC mixtures with MetS and its components were observed by utilizing multiple statistical models and large-scale national data. These findings may serve as the theoretical basis for future experimental and mechanistic studies and have important implications for public health.
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