Evidence map›Paper›PMID 38431463›Full record

ReviewSeminars in hematology2024

TET2 mutation as prototypic clonal hematopoiesis lesion.

Luca Guarnera, Babal K Jha

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Luca GuarneraDepartment of Biomedicine and Prevention, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Rome, Italy; Department of Translational Haematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.
Babal K JhaDepartment of Translational Haematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH; Center for Immunotherapy and Precision Immuno-Oncology (CITI), Lerner Research Institute (LRI) Cleveland Clinic, Cleveland, OH. Electronic address: jhab@ccf.org.
Cleveland Clinic · USUniversity of Rome Tor Vergata · IT

Funding

Eltombopag: Novel Mode of Action on Normal and Aplastic Anemia Hematopoietic Stem CellsR01DK131923 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI Babal K Jha, Jaroslaw P. Maciejewski · 2022 to 2026
$3.3M
Targeting TET DNA Dioxygenases as Therapeutic Principle in Myeloid NeoplasmsR01CA257544 · NCI · CLEVELAND CLINIC LERNER COM-CWRU · PI JHA, BABAL K, MACIEJEWSKI, JAROSLAW P. · 2021 to 2025
$3.0M
NCI NIH HHS R01 CA257544NIDDK NIH HHS R01 DK131923
6 · The paper itself

Abstract

Loss of function TET2 mutation (TET2

Indexed as

Clonal HematopoiesisDioxygenasesCell DifferentiationDNA-Binding ProteinsDNA MethylationHematopoiesisHumansMixed Function OxygenasesMutationProto-Oncogene ProteinsDioxygenasesDNA-Binding ProteinsMixed Function OxygenasesProto-Oncogene ProteinsTET1 protein, humanTET2 protein, humanAgingCHIPEpigeneticsInflammationTargetingTET2Therapeutic development

Identifiers

PMID38431463
PMCPMC10978279
OpenAlexW4391484481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.