ReviewTrends in cognitive sciences2024
Sedentary behavior and lifespan brain health.
Abstract readReview
In one paragraph
Review in Trends in cognitive sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 3 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Acute cognitive effects of interruptions to prolonged sitting with brief standing or physical activity breaks: a systematic review and three-level meta-analysis.The international journal of behavioral nutrition and physical activity · 2026Pooled it
- Acute effects of physical activity breaking up sedentary behavior on cognitive function, biological mechanisms, and practical recommendations: a systematic review.Frontiers in psychology · 2026Pooled it
- Effects of exercise interventions on cognitive function in sedentary adults: a systematic review and network meta-analysis.Frontiers in public health · 2026Pooled it
- Trial
- Effects of Physical Exercise Breaks on Executive Function in a Simulated Classroom Setting: Uncovering a Window into the Brain.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Trial
- Not all sitting is equal: Novel neuroimaging insights into mentally passive versus active sedentary behaviors.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Cognitively engaging sedentary activities are associated with better cognitive function in middle-aged adults: a cross-sectional study using the 1970 British Cohort Study.Journal of activity, sedentary and sleep behaviors · 2026Article
- Examining the clustering of lifestyle factors and affect in daily life: An idiographic approach.Applied psychology. Health and well-being · 2026Article
- Associations of distinct sedentary behaviors with cortical, subcortical, and white matter hyperintensity volumes: Evidence from the ARIC study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Trends and Behavioral Correlates of Excessive Screen Time Among Swedish Adolescents: A Repeated Cross-Sectional Study (2017-2023).Addictive behaviors reports · 2026Article
- Physical Fitness and Cognitive Performance in Preschool Children: Cross-Sectional and Longitudinal Associations From the ELFIT Trial.Scandinavian journal of medicine & science in sports · 2026Article
- Prospective association of device-based physical activity and sedentary time during childhood with mental health outcomes during adolescence.Child and adolescent mental health · 2026Article
- Not just how much, but how it's done: movement activity bout distributions and everyday cognition in older adults with elevated dementia risk.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Article
- Longitudinal associations between sedentary behavior types and mathematics ability mediated by externalizing and internalizing problems.NPJ science of learning · 2026Article
- Causal relationships between somatic movement, brain structures, and mental well-being: A multi-stage Mendelian randomization study.Psychological medicine · 2026Article
- Effects of videos with whole-body movements on young children's geography learning.NPJ science of learning · 2026Article
- The associations between sedentary behavior and cognition in a population cohort of older adults.Journal of Alzheimer's disease : JAD · 2026Article
- Effects of exercise snacks on physical and mental health among sedentary students: a randomized controlled trial study protocol.Frontiers in psychiatry · 2026Article
- Association between cognitive leisure activities and symptoms of depression in Chinese middle-aged and older adults: A CHARLS cohort study from 2011 to 2018.Global mental health (Cambridge, England) · 2026Article
- Psychosocial factors associated with physical activity and sedentary behavior in adolescents: evidence from physical education contexts in Quito.Frontiers in psychology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Liye ZouBody-Brain-Mind Laboratory, School of Psychology, Shenzhen University, Shenzhen, China. Electronic address: liyezou123@gmail.com.
Fabian HeroldBody-Brain-Mind Laboratory, School of Psychology, Shenzhen University, Shenzhen, China; Research Group Degenerative and Chronic Diseases, Movement, Faculty of Health Sciences Brandenburg, University of Potsdam, 14476 Potsdam, Germany.
Boris ChevalDepartment of Sport Sciences and Physical Education, Ecole Normale Supérieure Rennes, Bruz, France; Laboratory VIPS2, University of Rennes, Rennes, France.
Michael J WheelerPhysical Activity Laboratory, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia; Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia.
Dominika M PindusKinesiology and Community Health, University of Illinois at Chicago, Chicago, IL, USA; Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Neuroscience Program, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
Kirk I EricksonAdventHealth Research Institute, Department of Neuroscience, AdventHealth, Orlando, FL, USA; Department of Psychology, University of Pittsburgh, Pittsburgh, PA, USA; Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA, USA.
David A RaichlenHuman and Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA; Department of Anthropology, University of Southern California, Los Angeles, CA 90089, USA.
Gene E AlexanderBIO5 Institute, University of Arizona, Tucson, AZ 85721, USA; Department of Psychology, University of Arizona, Tucson, AZ 85721, USA; Evelyn F. McKnight Brain Institute, University of Arizona, Tucson, AZ 85721, USA; Department of Psychiatry, University of Arizona, Tucson, AZ 85721, USA; Neuroscience Graduate Interdisciplinary Program, University of Arizona, Tucson, AZ 85721, USA; Physiological Sciences Graduate Interdisciplinary Program, University of Arizona, Tucson, AZ85721, USA.
Notger G MüllerResearch Group Degenerative and Chronic Diseases, Movement, Faculty of Health Sciences Brandenburg, University of Potsdam, 14476 Potsdam, Germany.
David W DunstanPhysical Activity Laboratory, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia; Institute for Physical Activity and Nutrition (IPAN), School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia.
Arthur F KramerBeckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA; Center for Cognitive and Brain Health, Northeastern University, Boston, MA, USA; Department of Psychology, Northeastern University, Boston, MA, 02115, USA.
Charles H HillmanCenter for Cognitive and Brain Health, Northeastern University, Boston, MA, USA; Department of Psychology, Northeastern University, Boston, MA, 02115, USA; Department of Physical Therapy, Movement, & Rehabilitation Sciences, Northeastern University, Boston, MA, 02115, USA.
Mats HallgrenEpidemiology of Psychiatric Conditions, Substance Use and Social Environment (EPiCSS), Department of Public Health Sciences, Karolinska Institutet, Solna, Sweden.
Ulf EkelundDepartment of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway; Department of Chronic Diseases and Ageing, The Norwegian Institute for Public Health, Oslo, Norway.
Silvio MaltagliatiHuman and Evolutionary Biology Section, Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Neville OwenPhysical Activity Laboratory, Baker Heart & Diabetes Institute, Melbourne, Victoria, Australia; Centre for Urban Transitions, Swinburne University of Technology, Melbourne, Victoria, Australia.
Funding
Research Education ComponentP30AG019610 · NIA · SUN HEALTH RESEARCH INSTITUTE · PI GONZALEZ HERNANDEZ, GRACIELA · 2001 to 2020
$32.5MResearch Education ComponentP30AG072980 · NIA · BANNER HEALTH · PI HEATHER Allyson BIMONTE-NELSON · 2021 to 2026
$24.9MRevitalizing Cognition in Older Adults at Risk for Alzheimer's Disease with Near-Infrared Photobiomodulation: Diversity SupplementR01AG064587 · NIA · UNIVERSITY OF FLORIDA · PI ALEXANDER, GENE E, BOWERS, DAWN · 2019 to 2023
$4.0MInactivity, sedentary behavior, and the risk for Alzheimer’s disease in middle aged to older adultsR01AG072445 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GENE E ALEXANDER, Yann Charles Klimentidis · 2022 to 2026
$3.3MPhysical activity predictors of cognitive and brain health in the risk for Alzheimer's diseaseR56AG067200 · NIA · UNIVERSITY OF ARIZONA · PI ALEXANDER, GENE E, RAICHLEN, DAVID · 2020 to 2020
$767kNIA NIH HHS P30 AG019610NIA NIH HHS P30 AG072980NIA NIH HHS R01 AG064587NIA NIH HHS R01 AG072445NIA NIH HHS R56 AG067200
Abstract
Higher levels of physical activity are known to benefit aspects of brain health across the lifespan. However, the role of sedentary behavior (SB) is less well understood. In this review we summarize and discuss evidence on the role of SB on brain health (including cognitive performance, structural or functional brain measures, and dementia risk) for different age groups, critically compare assessment approaches to capture SB, and offer insights into emerging opportunities to assess SB via digital technologies. Across the lifespan, specific characteristics of SB (particularly whether they are cognitively active or cognitively passive) potentially act as moderators influencing the associations between SB and specific brain health outcomes. We outline challenges and opportunities for future research aiming to provide more robust empirical evidence on these observations.
Indexed as
LongevitySedentary BehaviorBrainExerciseHumansadolescentsagingchildrencognitiondementiaprolonged sitting
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.