Evidence map›Paper›PMID 38431383›Full record

ArticleJournal of molecular and cellular cardiology2024

Modeling ionizing radiation-induced cardiovascular dysfunction with human iPSC-derived engineered heart tissues.

Xu Cao, Dilip Thomas, Luke A Whitcomb, Mingqiang Wang, Anushree Chatterjee, Adam J Chicco, Michael M Weil, Joseph C Wu

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular and cellular cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xu CaoStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, United States of America; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States of America.
Dilip ThomasStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, United States of America; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States of America.
Luke A WhitcombDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States of America.
Mingqiang WangStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, United States of America; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States of America.
Anushree ChatterjeeDepartment of Chemical and Biological Engineering, University of Colorado Boulder, Boulder, CO 80303, United States of America.
Adam J ChiccoDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States of America. Electronic address: adam.chicco@colostate.edu.
Michael M WeilDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, United States of America. Electronic address: michael.weil@colostate.edu.
Joseph C WuStanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, United States of America; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, United States of America; Greenstone Biosciences, Palo Alto, CA 94304, United States of America. Electronic address: joewu@stanford.edu.

Funding

Modeling Tyrosine Kinase Inhibitor-Induced Vascular Dysfunction Using Human iPSCsR01HL141851 · NHLBI · STANFORD UNIVERSITY · PI WONG, WING H., WU, JOSEPH C. · 2018 to 2025
$5.7M
Single Cell Sequencing of Human iPSC-CM Subtype Identity and FunctionR01HL145676 · NHLBI · STANFORD UNIVERSITY · PI MARK MERCOLA, Joseph C. Wu · 2019 to 2026
$5.1M
Elucidating Anthracycline-Induced Cell Type-Specific Cardiovascular Toxicity with CRISPRi/a ScreensR01HL150693 · NHLBI · STANFORD UNIVERSITY · PI Ronglih Liao, Joseph C. Wu · 2021 to 2026
$4.1M
Modeling Susceptibility to Radiation Therapy-induced Cardiotoxicity Using Cell Village iPSCsR01HL171102 · NHLBI · STANFORD UNIVERSITY · PI MARK MERCOLA, Joseph C. Wu · 2024 to 2026
$2.1M
Effect of Microgravity on Drug Responses Using Engineered Heart TissuesUH3TR002588 · NCATS · STANFORD UNIVERSITY · PI PRUITT, BETH L, WU, JOSEPH C. · 2020 to 2022
$1.6M
Unraveling Adverse Effects of Checkpoint Inhibitors Using iPSC-derived Cardiac OrganoidsK99HL163443 · NHLBI · STANFORD UNIVERSITY · PI THOMAS, DILIP · 2023 to 2024
$249k
NCATS NIH HHS UH3 TR002588NHLBI NIH HHS K99 HL163443NHLBI NIH HHS R01 HL141851NHLBI NIH HHS R01 HL145676NHLBI NIH HHS R01 HL150693NHLBI NIH HHS R01 HL171102
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Induced Pluripotent Stem CellsCell DifferentiationHumansMyocytes, CardiacRadiation, IonizingEngineered heart tissueHuman induced pluripotent stem cellIonizing radiationRadiation-induced heart diseaseγ-Rays

Identifiers

PMID38431383
PMCPMC10961094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.