SynthesisArchives of orthopaedic and trauma surgery2024
High survivorship rate and good clinical outcomes after high tibial osteotomy in patients with radiological advanced medial knee osteoarthritis: a systematic review.
Synthesis in Archives of orthopaedic and trauma surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Effectiveness and user experiences of a valgus brace in patients with knee osteoarthritis: A mixed-method randomised controlled trial.PloS one · 2025Trial
- Equal rates of bone healing and reduced surgical time with iliac crest allograft compared to autograft in medial opening wedge high tibial osteotomy: a randomized controlled clinical trial.Archives of orthopaedic and trauma surgery · 2024Trial
- Ankle Alignment Changes After High Tibial Osteotomy due to Valgus-Shaped Distal Tibia.Cartilage · 2026Article
- Medial open-wedge high tibial osteotomy demonstrates an 85.9% non-conversion rate and 76.8% patient satisfaction at a minimum follow-up of 10 years.Journal of experimental orthopaedics · 2026Article
- Does postoperative alignment influence outcome after medial opening wedge high tibial osteotomy? A long-term follow-up study.International orthopaedics · 2026Article
- Complications and Reoperation Rates of Total Knee Arthroplasty After High Tibial Osteotomy: A Matched Cohort Analysis From a Nationwide Database.Arthroplasty today · 2026Article
- Excessive tibial valgus was not associated with worse 5-year clinical outcomes after medial opening-wedge high tibial osteotomy for advanced knee osteoarthritis: a retrospective cohort study.Frontiers in surgery · 2026Article
- Medial Opening-Wedge High Tibial Osteotomy Delivers Meaningful Early Outcomes Even in KL-3 Osteoarthritis: A 24-Month Stratified Cohort Analysis.Sisli Etfal Hastanesi tip bulteni · 2026Article
- High survival rates and patient satisfaction 12 years after medial open wedge high tibial osteotomy surgery: A prospective cohort study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2025Article
- CORR Insights®: Does Periacetabular Osteotomy Affect the Load Distribution on the Knee?Clinical orthopaedics and related research · 2025Article
- Reasons for refusing high tibial osteotomy and the impact of virtual reality-based patient education: a prospective single-centre study.Journal of orthopaedic surgery and research · 2025Article
- Beneficial effect of medial opening wedge high tibial osteotomy on mental health of patients with knee osteoarthritis.Journal of experimental orthopaedics · 2025Article
- Combined High Tibial Osteotomy and Transtibial Drilling of Tibial and Femoral Medial Compartment Cartilage Defect of the Knee.Arthroscopy techniques · 2025Article
- Article
- Achieving Sufficient Valgus Alignment is Essential to Ensure Low Residual Pain in Short- to Midterm Follow-up After High Tibial Osteotomy in KL Grade 4 Osteoarthritis Patients.Orthopaedic journal of sports medicine · 2025Article
- Treatment of osteoarthritic knee with high tibial osteotomy and allogeneic human umbilical cord blood-derived mesenchymal stem cells combined with hyaluronate hydrogel composite.Stem cell research & therapy · 2025Observational
- Knee osteotomies are becoming widely accepted and increasingly used, but rehabilitation techniques still vary widely between surgeons: A survey on current trends.Journal of experimental orthopaedics · 2025Article
- Targeting p21-Positive Senescent Chondrocytes via IL-6R/JAK2 Inhibition to Alleviate Osteoarthritis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Comparison of clinical outcomes among patients treated with high tibial osteotomy and meniscal repair of degenerative medial meniscal tear with mild varus deformity.Archives of orthopaedic and trauma surgery · 2025Article
- 5-Year Results of an Implantable Shock Absorber Demonstrate Durable Outcomes in Patients with Medial Knee Osteoarthritis.JB & JS open accessArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe role of valgus producing high tibial osteotomy (HTO) for the treatment of advanced knee osteoarthritis (OA) is still controversial. The aim of the current systematic review was to assess survivorship and patient-reported outcomes (PROMs) of high tibial osteotomy in patients with radiological advanced medial knee OA.
methodsA systematic search of PubMed, Cochrane and EMBASE database was performed in July 2023 in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) guidelines. Inclusion and exclusion criteria were applied to identify studies investigating the survivorship rate and PROMs of valgus-producing high tibial osteotomy in patients with advanced knee OA at x-ray assessment in the medial compartment at minimum-two-years follow up. Advanced radiological OA was defined as Kellgren Lawrence (K-L) ≥ 3 or Ahlbäch ≥ 2. Survivorship was defined as percentage of patients free of total knee arthroplasty (TKA) at follow-up. Clinical interpretation of provided PROMs were performed according to minimal clinically important difference (MCID) and patient acceptable symptom state (PASS) target values reported in literature. Survivorship data and PROMs scores were extracted, and studies were stratified based on selected study features. The quality of included studies was assessed with modified Coleman score.
resultsA total of 18 studies, totalling 1296 knees with a mean age between 46.9 and 67 years old, were included. Average survivorship was of 74.6% (range 60 - 98.1%) at 10-years follow up. The subjective scoring systems showed good results according to MCID and PASS, and postoperative improvements were partially maintained until final follow-up.
conclusionHTO is worth considering as treatment choice even in patients affected by radiological advanced medial knee osteoarthritis. Long term survivorship and good patient reported clinical outcomes could be expected in this population. LEVEL OF EVIDENCE: IV; systematic review of level III-IV studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.