Evidence map›Paper›PMID 38429653›Full record

ArticleBMC cancer2024

Convolutional neural network applied to preoperative venous-phase CT images predicts risk category in patients with gastric gastrointestinal stromal tumors.

Jian Wang, Meihua Shao, Hongjie Hu, Wenbo Xiao, Guohua Cheng, Guangzhao Yang, Hongli Ji, Susu Yu, Jie Wan, Zongyu Xie and 1 more

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Jian Wang *Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Meihua Shao *Department of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Hongjie HuDepartment of Radiology, The Sir Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Wenbo XiaoDepartment of radiology,The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Guohua ChengJianpei Technology, Hangzhou, Zhejiang, China.
Guangzhao YangDepartment of Radiology, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, China.
Hongli JiJianpei Technology, Hangzhou, Zhejiang, China.
Susu YuDepartment of radiology,The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Jie WanJianpei Technology, Hangzhou, Zhejiang, China.
Zongyu XieDepartment of Radiology, The First Affliated Hospital of Bengbu Medical University, Bengbu, Anhui, China.
Maosheng XuDepartment of radiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, China. xums166@zcmu.edu.cn.
First Affiliated Hospital Zhejiang University · CNTongde Hospital of Zhejiang Province · CNZhejiang Chinese Medical University · CNFirst Affiliated Hospital of Bengbu Medical College · CNSir Run Run Shaw Hospital · CN

Funding

Zhejiang Provincial Natural Science Foundation of China No.LGF21H030004
6 · The paper itself

Abstract

objectiveThe risk category of gastric gastrointestinal stromal tumors (GISTs) are closely related to the surgical method, the scope of resection, and the need for preoperative chemotherapy. We aimed to develop and validate convolutional neural network (CNN) models based on preoperative venous-phase CT images to predict the risk category of gastric GISTs.

methodA total of 425 patients pathologically diagnosed with gastric GISTs at the authors' medical centers between January 2012 and July 2021 were split into a training set (154, 84, and 59 with very low/low, intermediate, and high-risk, respectively) and a validation set (67, 35, and 26, respectively). Three CNN models were constructed by obtaining the upper and lower 1, 4, and 7 layers of the maximum tumour mask slice based on venous-phase CT Images and models of CNN_layer3, CNN_layer9, and CNN_layer15 established, respectively. The area under the receiver operating characteristics curve (AUROC) and the Obuchowski index were calculated to compare the diagnostic performance of the CNN models.

resultsIn the validation set, CNN_layer3, CNN_layer9, and CNN_layer15 had AUROCs of 0.89, 0.90, and 0.90, respectively, for low-risk gastric GISTs; 0.82, 0.83, and 0.83 for intermediate-risk gastric GISTs; and 0.86, 0.86, and 0.85 for high-risk gastric GISTs. In the validation dataset, CNN_layer3 (Obuchowski index, 0.871) provided similar performance than CNN_layer9 and CNN_layer15 (Obuchowski index, 0.875 and 0.873, respectively) in prediction of the gastric GIST risk category (All P >.05).

conclusionsThe CNN based on preoperative venous-phase CT images showed good performance for predicting the risk category of gastric GISTs.

Indexed as

Gastrointestinal Stromal TumorsStomach NeoplasmsHumansNeural Networks, ComputerROC CurveTomography, X-Ray ComputedComputed tomographyConvolutional neural networkGastric stromal tumors

Identifiers

PMID38429653
PMCPMC10908217
OpenAlexW4392388124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.