Evidence map›Paper›PMID 38429572›Full record

ArticleSurgical endoscopy2024

Risk factors for positive resection margins after endoscopic resection for gastrointestinal neuroendocrine tumors.

Liu Han, Jianglei Li, Chengbai Liang, Yi Chu, Yongjun Wang, Liang Lv, Deliang Liu, Yuyong Tan

Abstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Step-by-Step Approach to the Incidental Diagnosis of Type I Gastric Neuroendocrine Tumors: Practical Insights.JGH open : an open access journal of gastroenterology and hepatology · 2025
    Review
  5. Review
  6. Long-Term Outcomes in Patients With Non-Ampullary Duodenal Neuroendocrine Tumors.The Korean journal of helicobacter and upper gastrointestinal research · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Liu Han *Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Jianglei Li *Department of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Chengbai LiangDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Yi ChuDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Yongjun WangDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Liang LvDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
Deliang LiuDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China. deliangliu@csu.edu.cn.
Yuyong TanDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China. tanyuyong@csu.edu.cn.ORCID 0000-0002-0571-3136
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn recent years, the incidence of gastrointestinal neuroendocrine tumors (GI-NETs) has remarkably increased due to the widespread use of screening gastrointestinal endoscopy. Currently, the most common treatments are surgery and endoscopic resection. Compared to surgery, endoscopic resection possesses a higher risk of resection margin residues for the treatment of GI-NETs.

methodsA total of 315 patients who underwent surgery or endoscopic resection for GI-NETs were included. We analyzed their resection modality (surgery, ESD, EMR), margin status, Preoperative marking and Prognosis.

resultsAmong 315 patients included, 175 cases underwent endoscopic resection and 140 cases underwent surgical treatment. A total of 43 (43/175, 24.57%) and 10 (10/140, 7.14%) patients exhibited positive resection margins after endoscopic resection and surgery, respectively. Multivariate regression analysis suggested that no preoperative marking and endoscopic treatment methods were risk factors for resection margin residues. Among the patients with positive margin residues after endoscopic resection, 5 patients underwent the radical surgical resection and 1 patient underwent additional ESD resection. The remaining 37 patients had no recurrence during a median follow-up of 36 months.

conclusionsCompared with surgery, endoscopic therapy has a higher margin residual rate. During endoscopic resection, preoperative marking may reduce the rate of lateral margin residues, and endoscopic submucosal dissection may be preferred than endoscopic mucosal resection. Periodical follow-up may be an alternative method for patients with positive margin residues after endoscopic resection.

Indexed as

Endoscopic Mucosal ResectionGastrointestinal NeoplasmsNeuroendocrine TumorsRectal NeoplasmsHumansIntestinal MucosaMargins of ExcisionRetrospective StudiesRisk FactorsTreatment OutcomeEMREndoscopyESDGastrointestinal neuroendocrine tumorsPositive resection margins

Identifiers

PMID38429572
OpenAlexW4392388419

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.