Evidence map›Paper›PMID 38429201›Full record

ArticleSeminars in hematology2024

Clonal hematopoiesis in the setting of hematopoietic cell transplantation.

Christopher J Gibson, R Coleman Lindsley, Lukasz P Gondek

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Seminars in hematology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
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  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Christopher J GibsonDivision of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA.
R Coleman LindsleyDivision of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA.
Lukasz P GondekDivision of Hematologic Malignancies, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD. Electronic address: lgondek1@jhmi.edu.
Dana-Farber Cancer Institute · USJohns Hopkins University · US

Funding

Single Cell and ImmunogenomicsP01CA229092 · NCI · DANA-FARBER CANCER INST · PI KIM, HAESOOK T · 2019 to 2023
$13.8M
The Biological Consequences of Age-related Clonal HematopoiesisR01HL156144 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI GONDEK, LUKASZ PAWEL · 2021 to 2025
$2.0M
NCI NIH HHS P01 CA229092NHLBI NIH HHS R01 HL156144
6 · The paper itself

Abstract

Clonal hematopoiesis (CH) in autologous transplant recipients and allogeneic transplant donors has genetic features and clinical associations that are distinct from each other and from non-cancer populations. CH in the setting of autologous transplant is enriched for mutations in DNA damage response pathway genes and is associated with adverse outcomes, including an increased risk of therapy-related myeloid neoplasm and inferior overall survival. Studies of CH in allogeneic transplant donors have yielded conflicting results but have generally shown evidence of potentiated alloimmunity in recipients, with some studies showing an association with favorable recipient outcomes.

Indexed as

Clonal HematopoiesisHematopoietic Stem Cell TransplantationHumansMyeloproliferative DisordersTransplantation, AutologousAllogeneic hematopoietic cell transplantationAutologous stem cell transplantationClonal hematopoiesisOutcome

Identifiers

PMID38429201
PMCPMC10978245
OpenAlexW4391426118

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.