Evidence map›Paper›PMID 38428979›Full record

ArticleRMD open2024

Validity of an ultrasonographic joint-specific scoring system in juvenile idiopathic arthritis: a cross-sectional study comparing ultrasound findings of synovitis with whole-body magnetic resonance imaging and clinical assessment.

Nina Krafft Sande, Eva Kirkhus, Vibke Lilleby, Anders Høye Tomterstad, Anna-Birgitte Aga, Berit Flatø, Pernille Bøyesen

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Whole-body MRI in arthritis.Skeletal radiology · 2025
    Review
  6. Article
  7. Review
  8. Sonographic and Disease Activity Findings Related With Medication Change in JIA: A Historical Cohort Study.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nina Krafft SandeDepartment of Rheumatology, Oslo University Hospital, Oslo, Norway ninamkrafft@hotmail.com.ORCID 0000-0003-3461-9525
Eva KirkhusDepartment of Radiology, Oslo University Hospital, Oslo, Norway.
Vibke LillebyDepartment of Rheumatology, Oslo University Hospital, Oslo, Norway.
Anders Høye TomterstadDepartment of Radiology, Oslo University Hospital, Oslo, Norway.
Anna-Birgitte AgaDepartment of Rheumatology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-0234-4993
Berit FlatøDepartment of Rheumatology, Oslo University Hospital, Oslo, Norway.
Pernille BøyesenDepartment of Rheumatology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-9751-5144
Oslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the validity of an ultrasonographic scoring system in juvenile idiopathic arthritis (JIA) by comparing ultrasound detected synovitis with whole-body MRI and clinical assessment of disease activity.

methodsIn a cross-sectional study, 27 patients with active JIA underwent clinical 71-joints examination, non-contrast enhanced whole-body MRI and ultrasound evaluation of 28 joints (elbow, radiocarpal, midcarpal, metacarpophalangeal 2-3, proximal interphalangeal 2-3, hip, knee, tibiotalar, talonavicular, subtalar and metatarsophalangeal 2-3). One rheumatologist, blinded to clinical findings, performed ultrasound and scored synovitis (B-mode and power Doppler) findings using a semiquantitative joint-specific scoring system for synovitis in JIA. A radiologist scored effusion/synovial thickening on whole-body MRI using a scoring system for whole-body MRI in JIA. At patient level, associations between ultrasound synovitis sum scores, whole-body MRI effusion/synovial thickening sum scores, clinical arthritis sum scores, and the 71-joints Juvenile Arthritis Disease Activity Score (JADAS71) were calculated using Spearman's correlation coefficients (r

resultsUltrasound synovitis sum scores strongly correlated with whole-body MRI effusion/synovial thickening sum scores (r

conclusionOur findings suggest that ultrasound is a valid instrument to detect synovitis, and that ultrasound synovitis sum scores can reflect disease activity and may be an outcome measure in JIA.

Indexed as

Arthritis, JuvenileSynovitisCross-Sectional StudiesHumansMagnetic Resonance ImagingWhole Body ImagingArthritis, JuvenileInflammationMagnetic Resonance ImagingSynovitisUltrasonography

Identifiers

PMID38428979
PMCPMC10910647
OpenAlexW4392360780

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.