Evidence map›Paper›PMID 38428746›Full record

ArticleDiabetes research and clinical practice2024

Relationships of hypoglycemia awareness, hypoglycemia beliefs, and continuous glucose monitoring glycemic profiles with anxiety and depression symptoms in adults with type 1 diabetes using continuous glucose monitoring systems.

Yu Kuei Lin, Emily Hepworth, Nicole de Zoysa, Jessica McCurley, Mary Ellen Vajravelu, Wen Ye, Gretchen A Piatt, Stephanie A Amiel, Simon J Fisher, Rodica Pop-Busui and 1 more

Open access · greenAbstract read
In one paragraph

Article in Diabetes research and clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Yu Kuei LinDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA. Electronic address: yuklin@med.umich.edu.
Emily HepworthDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA.
Nicole de ZoysaDepartment of Diabetes, King's College Hospital NHS Foundation Trust, London SE5 9RS, UK.
Jessica McCurleyDepartment of Psychology, San Diego State University, San Diego, CA 92182, USA.
Mary Ellen VajraveluCenter for Pediatric Research in Obesity and Metabolism, University of Pittsburgh School of Medicine, Pittsburgh, PA 15224, USA.
Wen YeDepartment of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI 48105, USA.
Gretchen A PiattDepartment of Learning Health Sciences, University of Michigan Medical School, Ann Arbor, MI 48105, USA.
Stephanie A AmielDepartment of Diabetes, School of Cardiovascular and Metabolic Medicine and Sciences, Kings College London, London SE5 9RJ, UK.
Simon J FisherDepartment of Internal Medicine, University of Kentucky College of Medicine, Lexington, KY 40508, USA.
Rodica Pop-BusuiDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA.
James E AikensDepartment of Family Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA.
University of Michigan · USKing's College Hospital NHS Foundation Trust · GBKing's College London · GBSan Diego State University · USUniversity of Kentucky · USUniversity of Pittsburgh · US

Funding

Regional Pilot And Feasibility Study Grants ProgramP30DK020572 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Scott Soleimanpour · 2013 to 2026
$24.3M
Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Pharmacological Approach to the Restoration of Hypoglycemia AwarenessR01DK118082 · NIDDK · UNIVERSITY OF UTAH · PI FISHER, SIMON J · 2019 to 2023
$1.9M
Be Well at Work-Plus: Engaging low-wage workers in the design and implementation of a depression and physical activity intervention - Administrative SupplementK23HL157763 · NHLBI · SAN DIEGO STATE UNIVERSITY · PI MCCURLEY, JESSICA LAUREN · 2021 to 2025
$1.0M
Minimizing Hypoglycemia in Adults with Type 1 Diabetes through an Integrated Mobile Health and Continuous Glucose Monitoring SystemK23DK129724 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LIN, YU KUEI · 2021 to 2025
$984k
NHLBI NIH HHS K23 HL157763NHLBI NIH HHS L30 HL170331NIDDK NIH HHS K23 DK129724NIDDK NIH HHS P30 DK020572NIDDK NIH HHS P30 DK092926NIDDK NIH HHS P30 DK111022NIDDK NIH HHS R01 DK118082
6 · The paper itself

Abstract

aimsTo evaluate relationships of hypoglycemia awareness, hypoglycemia beliefs, and continuous glucose monitoring (CGM) glycemic profiles with anxiety and depression symptoms in adults with type 1 diabetes (T1D) who use CGM.

methodsA cross-sectional survey and data collections were completed with 196 T1D adults who used CGM (59% also used automated insulin delivery devices (AIDs)). We assessed hypoglycemia awareness (Gold instrument), hypoglycemia beliefs (Attitudes to Awareness of Hypoglycemia instrument), CGM glycemic profiles, demographics, and anxiety and depression symptoms (Hospital Anxiety and Depression Scale). Analysis included simple and multiple linear regression analyses.

resultsLower hypoglycemia awareness, weaker "hypoglycemia concerns minimized" beliefs, stronger "hyperglycemia avoidance prioritized" beliefs were independently associated with higher anxiety symptoms (P < 0.05), with similar trends in both subgroups using and not using AIDs. Lower hypoglycemia awareness were independently associated with greater depression symptoms (P < 0.05). In participants not using AIDs, more time in hypoglycemia was related to less anxiety and depression symptoms (P < 0.05). Being female and younger were independently associated with higher anxiety symptoms, while being younger was also independently associated with greater depression symptoms (P < 0.05).

conclusionOur findings revealed relationships of impaired hypoglycemia awareness, hypoglycemia beliefs, CGM-detected hypoglycemia with anxiety and depression symptoms in T1D adults who use CGMs.

Indexed as

Diabetes Mellitus, Type 1HypoglycemiaAdultAnxietyBlood GlucoseBlood Glucose Self-MonitoringContinuous Glucose MonitoringCross-Sectional StudiesDepressionFemaleHumansHypoglycemic AgentsInsulinMaleBlood GlucoseHypoglycemic AgentsInsulinAnxietyContinuous glucose monitoringDepressionHypoglycemiaType 1 diabetes

Identifiers

PMID38428746
PMCPMC10960959
OpenAlexW4392247042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.