Evidence map›Paper›PMID 38428398›Full record

ArticleCell2024

Loss of epigenetic information as a cause of mammalian aging.

Jae-Hyun Yang, Motoshi Hayano, Patrick T Griffin, João A Amorim, Michael S Bonkowski, John K Apostolides, Elias L Salfati, Marco Blanchette, Elizabeth M Munding, Mital Bhakta and 54 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. AI platform for CRISPR functional mapping and function-based drug design.bioRxiv : the preprint server for biology · 2026
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Exercise attenuates the hallmarks of aging: Novel perspectives.Journal of sport and health science · 2025
    Review
  19. circHERC1-A telomerase activator.Science advances · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

64 authors.

Jae-Hyun Yang
Motoshi Hayano
Patrick T Griffin
João A Amorim
Michael S Bonkowski
John K Apostolides
Elias L Salfati
Marco Blanchette
Elizabeth M Munding
Mital Bhakta
Yap Ching Chew
Wei Guo
Xiaojing Yang
Sun Maybury-Lewis
Xiao Tian
Jaime M Ross
Giuseppe Coppotelli
Margarita V Meer
Ryan Rogers-Hammond
Daniel L Vera
Yuancheng Ryan Lu
Jeffrey W Pippin
Michael L Creswell
Zhixun Dou
Caiyue Xu
Sarah J Mitchell
Abhirup Das
Brendan L O'Connell
Sachin Thakur
Alice E Kane
Qiao Su
Yasuaki Mohri
Emi K Nishimura
Laura Schaevitz
Neha Garg
Ana-Maria Balta
Meghan A Rego
Meredith Gregory-Ksander
Tatjana C Jakobs
Lei Zhong
Hiroko Wakimoto
Jihad El Andari
Dirk Grimm
Raul Mostoslavsky
Amy J Wagers
Kazuo Tsubota
Stephen J Bonasera
Carlos M Palmeira
Jonathan G Seidman
Christine E Seidman
Norman S Wolf
Jill A Kreiling
John M Sedivy
George F Murphy
Richard E Green
Benjamin A Garcia
Shelley L Berger
Philipp Oberdoerffer
Stuart J Shankland
Vadim N Gladyshev
Bruce R Ksander
Andreas R Pfenning
Luis A Rajman
David A Sinclair

Funding

STRUCTURAL BASIS FOR EPIGENETICS IN AGING AND LONGEVITYP01AG031862 · NIA · WISTAR INSTITUTE · PI ADAMS, PETER D. · 2008 to 2022
$28.3M
NIA NIH HHS P01 AG031862
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.