Evidence map›Paper›PMID 38427627›Full record

ReviewACS biomaterials science & engineering2024

Revolutionizing Cancer Treatment: The Promising Horizon of Zein Nanosystems.

Subham Preetam, Deb Duhita Mondal, Nobendu Mukerjee, Shaikh Sheeran Naser, Tanveer A Tabish, Nanasaheb Thorat

Abstract readReview
In one paragraph

Review in ACS biomaterials science & engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Fully bio-based wood adhesives from lignin and zein protein.Green chemistry : an international journal and green chemistry resource : GC · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Zein Nanoparticles Loaded withNanomaterials (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Subham PreetamDepartment of Robotics and Mechatronics Engineering, Daegu Gyeongbuk Institute of Science and Technology, Daegu 42988, South Korea.ORCID 0000-0002-5992-4609
Deb Duhita MondalDepartment of Biotechnology, Heritage Institute of Technology, Kolkata, West Bengal 700107, India.
Nobendu MukerjeeCentre for Global Health Research, Saveetha Medical College and Hospital, Chennai 602105, India.ORCID 0000-0002-7129-7003
Shaikh Sheeran NaserKSBT, Kalinga Institute of Industrial Technology, Bhubaneswar 751024, India.
Tanveer A TabishDivision of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7BN, United Kingdom.
Nanasaheb ThoratNuffield Department of Women's & Reproductive Health, Medical Science Division, John Radcliffe Hospital University of Oxford, Oxford, OX3 9DU, United Kingdom.ORCID 0000-0001-6343-527X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Various nanomaterials have recently become fascinating tools in cancer diagnostic applications because of their multifunctional and inherent molecular characteristics that support efficient diagnosis and image-guided therapy. Zein nanoparticles are a protein derived from maize. It belongs to the class of prolamins possessing a spherical structure with conformational properties similar to those of conventional globular proteins like ribonuclease and insulin. Zein nanoparticles have gained massive interest over the past couple of years owing to their natural hydrophilicity, ease of functionalization, biodegradability, and biocompatibility, thereby improving oral bioavailability, nanoparticle targeting, and prolonged drug administration. Thus, zein nanoparticles are becoming a promising candidate for precision cancer drug delivery. This review highlights the clinical significance of applying zein nanosystems for cancer theragnostic─moreover, the role of zein nanosystems for cancer drug delivery, anticancer agents, and gene therapy. Finally, the difficulties and potential uses of these NPs in cancer treatment and detection are discussed. This review will pave the way for researchers to develop theranostic strategies for precision medicine utilizing zein nanosystems.

Indexed as

Antineoplastic AgentsNeoplasmsZeinDrug CarriersDrug Delivery SystemsHumansAntineoplastic AgentsDrug CarriersZeinanticancer therapydrug delivery systemprecision medicinezein nanoparticles

Identifiers

PMID38427627
PMCPMC11005017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.