Evidence map›Paper›PMID 38427364›Full record

ArticleJournal of musculoskeletal & neuronal interactions2024

Motor improvement in children with PMM2-CDG syndrome following a six-month rehabilitation treatment utilising whole-body vibration; a retrospective study.

Christiane Bossier, Christina Stark, Kyriakos Martakis, Ibrahim Duran, Eckhard Schoenau

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of musculoskeletal & neuronal interactions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Christiane BossierCenter of Prevention and Rehabilitation, Medical Faculty and University Hospital, University of Cologne, UniReha, Germany.
Christina StarkDepartment of Neurology, Medical Faculty and University Hospital, University of Frankfurt/Main, Germany.
Kyriakos MartakisDepartment of Pediatrics, Medical Faculty and University Hospital, University of Cologne, Germany.
Ibrahim DuranCenter of Prevention and Rehabilitation, Medical Faculty and University Hospital, University of Cologne, UniReha, Germany.
Eckhard SchoenauCenter of Prevention and Rehabilitation, Medical Faculty and University Hospital, University of Cologne, UniReha, Germany.
University Hospital Cologne · DEGoethe University Frankfurt · DEUniversity Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to assess the effect of a six-month interval rehabilitation treatment on motor function of children with PMM2-CDG syndrome (#212065 Congenital disorder of glycosylation, Type Ia; CDG1A, OMIM catalogue number).

methodsThe concept 'Auf die Beine' (Center for Prevention and Rehabilitation of the University of Cologne, Germany) combines two short inpatient stays (1 to 2 weeks) with a six-month whole-body vibration (WBV) home-training program. 13 patients with PMM2-CDG syndrome participated in this concept from 2006 until 2015. Assessments at start, six months and 12 months (follow-up): Gross Motor Function Measure (GMFM-66), One-Minute Walk Test (1MWT) and instrumented gait analyses.

resultsThe GMFM-66 (9 of 13 children) improved by 5.3 (mean) points (SD 3.2) at 12 months (p=0.0039). The 1MWT (6 of 13 children) improved by 19.17 meter (SD 16.51) after 12 months (p=0.0313). Gait analysis (9 of 13 children) measured by pathlength/distance ratio improved by -0.8 (SD 1.9) at 12 months (p=0.0195).

conclusionPatients with PMM2-CDG syndrome benefit from the interval rehabilitation program 'Auf die Beine' including WBV.

Indexed as

Congenital Disorders of GlycosylationPhosphotransferases (Phosphomutases)ChildHumansRetrospective StudiesSyndromeVibrationPhosphotransferases (Phosphomutases)ChildrenPhysiotherapyPMM2-CDG SyndromeRehabilitationWhole-body Vibration

Identifiers

PMID38427364
PMCPMC10910202
OpenAlexW4394765756

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.