Evidence map›Paper›PMID 38427346›Full record

ArticleDiabetes care2024

Natural History of Type 2 Diabetes in Indians: Time to Progression.

K M Venkat Narayan, Dimple Kondal, Howard H Chang, Deepa Mohan, Unjali P Gujral, Ranjit Mohan Anjana, Lisa R Staimez, Shivani A Patel, Mohammed K Ali, Dorairaj Prabhakaran and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
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  7. Article
  8. Foods (Basel, Switzerland) · 2025
    Article
  9. Review
  10. Article
  11. Article
  12. The Prediabetes Wake-Up Call: Time for Proactive Endocrine Care.Indian journal of endocrinology and metabolism
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

K M Venkat NarayanEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA.ORCID 0000-0001-8621-5405
Dimple KondalPublic Health Foundation of India, New Delhi, India.ORCID 0000-0002-1417-9510
Howard H ChangEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA.ORCID 0000-0002-6316-1640
Deepa MohanMadras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialties Centre, Chennai, India.ORCID 0000-0001-6348-1946
Unjali P GujralEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA.ORCID 0000-0002-0352-813X
Ranjit Mohan AnjanaMadras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialties Centre, Chennai, India.ORCID 0000-0002-4843-1374
Lisa R StaimezEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA.ORCID 0000-0002-2818-1187
Shivani A PatelEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA.ORCID 0000-0003-0082-5857
Mohammed K AliEmory Global Diabetes Research Center, Woodruff Health Sciences Center and Emory University, Atlanta, GA.ORCID 0000-0001-7266-2503
Dorairaj PrabhakaranRollins School of Public Health, Emory University, Atlanta, GA.ORCID 0000-0002-3172-834X
Nikhil TandonAll India Institute of Medical Sciences, New Delhi, India.ORCID 0000-0003-4604-1986
Viswanathan MohanMadras Diabetes Research Foundation & Dr. Mohan's Diabetes Specialties Centre, Chennai, India.ORCID 0000-0001-5038-6210
Emory University · USMadras Diabetes Research Foundation · INAll India Institute of Medical Sciences · INCentre for Chronic Disease Control · IN

Funding

Translational Research Core - Engagement and Behavior ChangeP30DK111024 · NIDDK · EMORY UNIVERSITY · PI Mohammed Kumail Ali · 2016 to 2026
$13.4M
Spousal Influences on Subclinical and Clinical Vascular and Myocardial DiseaseP01HL154996 · NHLBI · EMORY UNIVERSITY · PI Kabayam M Venkat Narayan, ARSHED A QUYYUMI · 2022 to 2026
$13.4M
Worksite Lifestyle Program for Reducing Diabetes and Cardiovascular Risk in IndiaR01HL125442 · NHLBI · EMORY UNIVERSITY · PI PRABHAKARAN, DORAIRAJ, WEBER, MARY BETH · 2015 to 2019
$3.3M
Integrated Tracking, Referral, and Algorithmic Management (I-TREC) System for Hypertension and DiabetesU01HL138635 · NHLBI · ALL-INDIA INSTITUTE OF MEDICAL SCIENCES · PI TANDON, NIKHIL · 2017 to 2021
$1.3M
Health systems & implementation sciences institute for NCDs in SoAsia & LatinAmD43TW009135 · FIC · EMORY UNIVERSITY · PI LOZANO, RAFAEL, NARAYAN, KABAYAM M VENKAT · 2012 to 2016
$1.1M
FIC NIH HHS 5U01HL138635FIC NIH HHS D43 TW009135NHLBI NIH HHS HHSN268200900026CNHLBI NIH HHS P01 HL154996NHLBI NIH HHS R01 HL125442NHLBI NIH HHS U01 HL138635NIDDK NIH HHS P30 DK111024
6 · The paper itself

Abstract

objectiveTo describe the natural history of diabetes in Indians. RESEARCH DESIGN AND

methodsData are from participants older than 20 years in the Centre for Cardiometabolic Risk Reduction in South Asia longitudinal study. Glycemic states were defined per American Diabetes Association criteria. Markov models were used to estimate annual transition probabilities and sojourn time through states.

resultsAmong 2,714 diabetes-free participants, 641 had isolated impaired fasting glucose (iIFG), and 341 had impaired glucose tolerance (IGT). The annual transition to diabetes for those with IGT was 13.9% (95% CI 12.0, 15.9) versus 8.6% (7.3, 9.8) for iIFG. In the normoglycemia ↔ iIFG → diabetes model, mean sojourn time in normoglycemia was 40.3 (34.6, 48.2) years, and sojourn time in iIFG was 9.7 (8.4, 11.4) years. For the normoglycemia ↔ IGT → diabetes model, mean sojourn time in normoglycemia was 34.5 (29.5, 40.8) years, and sojourn time in IGT was 6.1 (5.3, 7.1) years.

conclusionsIndividuals reside in normoglycemia for 35-40 years; however, progression from prediabetes to diabetes is rapid.

Indexed as

Diabetes Mellitus, Type 2Glucose IntolerancePrediabetic StateBlood GlucoseHumansLongitudinal StudiesBlood Glucose

Identifiers

PMID38427346
PMCPMC11043225
OpenAlexW4392359371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.