Evidence map›Paper›PMID 38427308›Full record

SynthesisJournal of nephrology2024

Investigating the role of ultrasound-based shear wave elastography in kidney transplanted patients: correlation between non-invasive fibrosis detection, kidney dysfunction and biopsy results-a systematic review and meta-analysis.

Teodóra Filipov, Brigitta Teutsch, Anett Szabó, Attila Forintos, Júlia Ács, Alex Váradi, Péter Hegyi, Tibor Szarvas, Nándor Ács, Péter Nyirády and 1 more

Open access · hybridAbstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Kidney Elastography in Adult Nephrology: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026
    Review
  2. Review
  3. The application of shear wave elastography in monitoring renal allografts.Quantitative imaging in medicine and surgery · 2026
    Article
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  5. Article
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  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Teodóra FilipovDepartment of Interventional Radiology, Heart and Vascular Center, Faculty of Medicine, Semmelweis University, Határőr ut 18, 1122, Budapest, Hungary.
Brigitta TeutschCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Anett SzabóCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Attila ForintosCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Júlia ÁcsCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Alex VáradiCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Péter HegyiCentre for Translational Medicine, Semmelweis University, Budapest, Hungary.
Tibor SzarvasDepartment of Urology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Nándor ÁcsDepartment of Obstetrics and Gynecology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Péter NyirádyDepartment of Urology, Faculty of Medicine, Semmelweis University, Budapest, Hungary.
Pál Ákos DeákDepartment of Interventional Radiology, Heart and Vascular Center, Faculty of Medicine, Semmelweis University, Határőr ut 18, 1122, Budapest, Hungary. deakakos@gmail.com.ORCID 0000-0003-3881-837X
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInterstitial fibrosis and tubular atrophy are leading causes of renal allograft failure. Shear wave elastography could be a promising noninvasive method for providing information on the state of the kidney, with specific regard to fibrosis but currently available data in the literature are controversial. Our study aimed to analyze the correlation between shear wave elastography and various kidney dysfunction measures.

methodsThis review was registered on PROSPERO (CRD42021283152). We systematically searched three major databases (MEDLINE, Embase, and CENTRAL) for articles concerning renal transplant recipients, shear wave elastography, fibrosis, and kidney dysfunction. Meta-analytical calculations for pooled Pearson and Spearman correlation coefficients (r) were interpreted with 95% confidence intervals (CIs). Heterogeneity was tested with Cochran's Q test. I

resultsIn total, 16 studies were included in our meta-analysis. Results showed a moderate correlation between kidney stiffness and interstitial fibrosis and tubular atrophy, graded according to BANFF classification, on biopsy findings for pooled Pearson (r = 0.48; CI: 0.20, 0.69; I

conclusionOur results showed a moderate correlation between kidney stiffness measured by shear wave elastography and biopsy results. While noninvasive assessment of kidney fibrosis after transplantation is an important clinical goal, there is insufficient evidence to support the use of elastography over the performance of a kidney biopsy.

Indexed as

Elasticity Imaging TechniquesFibrosisKidneyKidney DiseasesKidney TransplantationBiopsyGlomerular Filtration RateHumansBiopsyRenal transplantationShear wave elastographySonoelastography

Identifiers

PMID38427308
PMCPMC11473454
OpenAlexW4392360022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.