Evidence map›Paper›PMID 38427242›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2024

Understanding Actin Remodeling in Neuronal Cells Through Podosomes.

Tazeen Qureshi, Smita Eknath Desale, Hariharakrishnan Chidambaram, Subashchandrabose Chinnathambi

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
8.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Podosomes and Mechanical Force.Results and problems in cell differentiation · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tazeen QureshiNeurobiology Group, Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Pune, India.
Smita Eknath DesaleNeurobiology Group, Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Pune, India.
Hariharakrishnan ChidambaramNeurobiology Group, Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Pune, India.
Subashchandrabose ChinnathambiNeurobiology Group, Division of Biochemical Sciences, CSIR-National Chemical Laboratory, Pune, India. subashneuro@nimhans.ac.in.ORCID 0000-0002-5468-2129
National Chemical Laboratory · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytoskeletal dysregulation forms an important aspect of many neurodegenerative diseases such as Alzheimer's disease. Cytoskeletal functions require the dynamic activity of the cytoskeletal proteins-actin, tubulin, and the associated proteins. One of such important phenomena is that of actin remodeling, which helps the cell to migrate, navigate, and interact with extracellular materials. Podosomes are complex actin-rich cytoskeletal structures, abundant in proteins that interact and degrade the extracellular matrix, enabling cells to displace and migrate. The formation of podosomes requires extensive actin networks and remodeling. Here we present a novel immunofluorescence-based approach to study actin remodeling in neurons through the medium of podosomes.

Indexed as

ActinsPodosomesActin CytoskeletonCytoskeletal ProteinsCytoskeletonExtracellular MatrixActinsCytoskeletal ProteinsActin remodelingAlzheimer’s diseaseCytoskeletonNeuronsPodosomes

Identifiers

PMID38427242
OpenAlexW4392394463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.