Evidence map›Paper›PMID 38427124›Full record

ArticleAIDS and behavior2024

Strategies to Close the PrEP Uptake Gap Among Transgender People and Men Who Have Sex with Men in Tshwane, South Africa: Perspectives from the Community.

India Perez-Urbano, Athmanundh Dilraj, Annah Pitsi, Naomi Hlongwane, Nada Abdelatif, Janan Dietrich, Khatija Ahmed

Open access · hybridAbstract read
In one paragraph

Article in AIDS and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

India Perez-UrbanoUniversity of California San Francisco School of Medicine, San Francisco, CA, 94143, USA. ip2443@cumc.columbia.edu.ORCID http://orcid.org/0000-0002-1218-3380
Athmanundh DilrajSetshaba Research Centre, Tshwane, Soshanguve, South Africa.
Annah PitsiSetshaba Research Centre, Tshwane, Soshanguve, South Africa.
Naomi HlongwaneSetshaba Research Centre, Tshwane, Soshanguve, South Africa.
Nada AbdelatifBiostatistics Research Unit, South African Medical Research Council, Cape Town, South Africa.
Janan DietrichPerinatal HIV Research Unit, University of Witwatersrand, Johannesburg, South Africa.
Khatija AhmedSetshaba Research Centre, Tshwane, Soshanguve, South Africa.
Setshaba Research Centre · ZASouth African Medical Research Council · ZATshwane University of Technology · ZAUniversity of California, San Francisco · US

Funding

LOC: HIV Vaccine Trials NetworkUM1AI068614 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Dan H. Barouch, Lawrence Corey · 2011 to 2026
$1175.6M
Soweto Clinical Trials UnitUM1AI069453 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI Glenda E Gray, Lerato Mohapi · 2012 to 2026
$40.9M
National Institute of Allergy and Infectious Diseases U.S. Public Health Service Grant UM1 AI068614NIAID NIH HHS UM1 AI068614NIAID NIH HHS UM1 AI069453
6 · The paper itself

Abstract

HIV Pre-exposure Prophylaxis (PrEP) uptake among transgender (TG) people and gay men and other men who have sex with men (MSM) remains low, despite South Africa being the first African country to approve PrEP. This mixed-methods study used a two-phase explanatory sequential design: (1) quantitative analysis of cross-sectional surveys followed by (2) qualitative in-depth interviews. This study explored facilitators and barriers to PrEP uptake to identify strategies to increase utilization in these key populations. We conducted 202 cross-sectional surveys and 20 in-depth interviews between July 2021 and March 2022 in Soshanguve, Tshwane, Gauteng. Quantitative data were analyzed using univariate logistic regression; thematic analysis was performed for qualitative data. Findings show high willingness to use PrEP but low PrEP uptake. We outline strategies to facilitate PrEP use: (1) demystify daily PrEP by deploying community-engaged PrEP education campaigns; (2) capitalize on existing peer networks; and (3) expand accessible and culturally responsive PrEP service delivery models. We provide feasible recommendations to close the PrEP uptake gap in these key populations in South Africa.

Indexed as

Anti-HIV AgentsHIV InfectionsHomosexuality, MalePre-Exposure ProphylaxisTransgender PersonsAdultCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansInterviews as TopicMaleMiddle AgedPatient Acceptance of Health CareQualitative ResearchSexual and Gender MinoritiesAnti-HIV AgentsHIV PreventionMen-who-have-sex-with-menMSMPre-exposure prophylaxisPrEPTransgender

Identifiers

PMID38427124
PMCPMC11161427
OpenAlexW4392357993

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.