ArticlePediatric nephrology (Berlin, Germany)2024
Comparison of estimated GFR using cystatin C versus creatinine in pediatric kidney transplant recipients.
Article in Pediatric nephrology (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 10 citations in OpenAlex.
- Comparison of different equations for estimating the glomerular filtration rate in pediatric kidney transplant recipients.Pediatric nephrology (Berlin, Germany) · 2026Article
- Diagnostic Accuracy of Eight Estimated Glomerular Filtration Rate Equations for Assessing Kidney Function in Korean Pediatric Patients.Annals of laboratory medicine · 2026Article
- Correlation Between Renal Biomarkers, Glomerular Filtration Rate, and Meropenem Clearance in Pediatric Septic Shock.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026Article
- Diagnostic performance of mDIXON-Quant imaging in assessing glomerulosclerosis severity for chronic kidney disease: a comparative study of R2* and fat fraction parameters.BMC medical imaging · 2026Article
- Which glomerular filtration rate estimation equations should be used in youth with type 1 diabetes?Pediatric nephrology (Berlin, Germany) · 2026Article
- Transition of patients with hereditary nephropathies from paediatric to adult care.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026Article
- Prognostic value of cystatin C for chronic kidney disease in pediatric urologic malformations.Pediatric research · 2026Article
- Biomarkers for Chronic Kidney Disease: An Updated Review of Innovative Detection Approaches.Current aging science · 2026Review
- A population pharmacokinetic approach to comparePediatric nephrology (Berlin, Germany) · 2025Article
- New equation for estimating glomerular filtration rate in Vietnamese kidney transplant recipients.International urology and nephrology · 2025Article
- The independent and interactive effects of heavy metal pollution and vitamin D deficiency on early kidney injury indicators: analysis of the National Health and Nutrition Examination Survey 2001-2004.BMC public health · 2025Article
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
Abstract
backgroundAn accurate, rapid estimate of glomerular filtration rate (GFR) in kidney transplant patients affords early detection of transplant deterioration and timely intervention. This study compared the performance of serum creatinine (Cr) and cystatin C (CysC)-based GFR equations to measured GFR (mGFR) using iohexol among pediatric kidney transplant recipients.
methodsCysC, Cr, and mGFR were obtained from 45 kidney transplant patients, 1-18 years old. Cr- and CysC-estimated GFR (eGFR) was compared against mGFR using the Cr-based (Bedside Schwartz, U25-Cr), CysC-based (Gentian CysC, CAPA, U25-CysC), and Cr-CysC combination (CKiD Cr-CysC, U25 Cr-CysC) equations in terms of bias, precision, and accuracy. Bland-Altman plots assessed the agreement between eGFR and mGFR. Secondary analyses evaluated the formulas in patients with biopsy-proven histological changes, and K/DOQI CKD staging.
resultsBias was small with Gentian CysC (0.1 ml/min/1.73 m
conclusionsIn this small cohort, CysC-based equations with or without Cr may have better bias, precision, and accuracy in predicting GFR.
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