Evidence map›Paper›PMID 38426280›Full record

ArticleHaematologica2024

Evidence for a cytoplasmic proplatelet promoting factor that triggers platelet production.

Joseph E Italiano, Kellie R Machlus

Abstract readLetter
In one paragraph

Article in Haematologica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Looking Under the Hood at the Cytoskeletal Engine of Platelet Production.Arteriosclerosis, thrombosis, and vascular biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Joseph E ItalianoVascular Biology Program, Department of Surgery, Boston Children's Hospital, 1 Blackfan Circle, Boston, Massachusetts, USA; Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts. Joseph.Italiano@childrens.harvard.edu.
Kellie R MachlusVascular Biology Program, Department of Surgery, Boston Children's Hospital, 1 Blackfan Circle, Boston, Massachusetts, USA; Harvard Medical School, 25 Shattuck Street, Boston, Massachusetts.

Funding

The Centrosome as a master controller of platelet production.R35HL161175 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI JOSEPH E ITALIANO · 2022 to 2026
$5.3M
The Biogenesis of Platelet-Derived Extracellular Vesicles and their Impact on Megakaryocyte MaturationR01HL151494 · NHLBI · BOSTON CHILDREN'S HOSPITAL · PI MACHLUS, KELLIE RAE · 2021 to 2025
$2.9M
Elucidation of the mechanisms by which fatty acids drive megakaryopoiesisR01DK139341 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI Kellie Rae Machlus · 2024 to 2026
$1.1M
The Role of CCL5 in Hematopoietic Stem Cell Activation and SkewingR03DK124746 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI MACHLUS, KELLIE RAE · 2021 to 2022
$266k
NHLBI NIH HHS R01 HL151494NHLBI NIH HHS R35 HL161175NIDDK NIH HHS R01 DK139341NIDDK NIH HHS R03 DK124746
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood PlateletsCytoplasmHumansThrombopoiesis

Identifiers

PMID38426280
PMCPMC11215393

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.