Evidence map›Paper›PMID 38426267›Full record

ArticlePediatrics2024

Causal Mediation of Neighborhood-Level Pediatric Hospitalization Inequities.

Cole Brokamp, Margaret N Jones, Qing Duan, Erika Rasnick Manning, Sarah Ray, Alexandra M S Corley, Joseph Michael, Stuart Taylor, Ndidi Unaka, Andrew F Beck and 1 more

Abstract read
In one paragraph

Article in Pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Diagnostic disparities in inborn errors of immunity: From clinical suspicion to diagnosis.The journal of allergy and clinical immunology. Global · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cole BrokampCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Margaret N JonesCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Qing DuanCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Erika Rasnick ManningCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Sarah RayUniversity of Cincinnati College of Medicine, Cincinnati, Ohio.
Alexandra M S CorleyCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Joseph MichaelCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Stuart TaylorCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Ndidi UnakaCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
Andrew F BeckCincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
RISEUP RESEARCH TEAM

Funding

Achieving Pediatric Health Equity by Responding to Identified Sociomedical risks with Effective Unified Purpose –Co-design and Evaluation of the RISEUP SystemR01HS027996 · AHRQ · CINCINNATI CHILDRENS HOSP MED CTR · PI BECK, ANDREW FINKEL · 2022 to 2025
$1.6M
AHRQ HHS R01 HS027996
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPopulation-wide racial inequities in child health outcomes are well documented. Less is known about causal pathways linking inequities and social, economic, and environmental exposures. Here, we sought to estimate the total inequities in population-level hospitalization rates and determine how much is mediated by place-based exposures and community characteristics.

methodsWe employed a population-wide, neighborhood-level study that included youth <18 years hospitalized between July 1, 2016 and June 30, 2022. We defined a causal directed acyclic graph a priori to estimate the mediating pathways by which marginalized population composition causes census tract-level hospitalization rates. We used negative binomial regression models to estimate hospitalization rate inequities and how much of these inequities were mediated indirectly through place-based social, economic, and environmental exposures.

resultsWe analyzed 50 719 hospitalizations experienced by 28 390 patients. We calculated census tract-level hospitalization rates per 1000 children, which ranged from 10.9 to 143.0 (median 45.1; interquartile range 34.5 to 60.1) across included tracts. For every 10% increase in the marginalized population, the tract-level hospitalization rate increased by 6.2% (95% confidence interval: 4.5 to 8.0). After adjustment for tract-level community material deprivation, crime risk, English usage, housing tenure, family composition, hospital access, greenspace, traffic-related air pollution, and housing conditions, no inequity remained (0.2%, 95% confidence interval: -2.2 to 2.7). Results differed when considering subsets of asthma, type 1 diabetes, sickle cell anemia, and psychiatric disorders.

conclusionsOur findings provide additional evidence supporting structural racism as a significant root cause of inequities in child health outcomes, including outcomes at the population level.

Indexed as

AsthmaHospitalizationAdolescentChildEnvironmental ExposureHumansResidence CharacteristicsRisk Factors

Identifiers

PMID38426267
PMCPMC12377460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.