Evidence map›Paper›PMID 38426232›Full record

ReviewObesity (Silver Spring, Md.)2024

Transforming Big Data into AI-ready data for nutrition and obesity research.

Diana M Thomas, Rob Knight, Jack A Gilbert, Marilyn C Cornelis, Marie G Gantz, Kate Burdekin, Kevin Cummiskey, Susan C J Sumner, Wimal Pathmasiri, Edward Sazonov and 5 more

Erratum issuedAbstract readReview
In one paragraph

Review in Obesity (Silver Spring, Md.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. A Systematic Review on Applications of Artificial Intelligence for Obesity Prevention.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
    Pooled it
  2. Review
  3. Review
  4. AI-readiness Criteria for Biomedical Data.bioRxiv : the preprint server for biology · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Diana M ThomasDepartment of Mathematical Sciences, United States Military Academy, West Point, New York, USA.ORCID 0000-0003-2641-9304
Rob KnightBioinformatics and Systems Biology Program, University of California San Diego, La Jolla, California, USA.
Jack A GilbertDepartment of Pediatrics and Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.
Marilyn C CornelisDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Marie G GantzBiostatics and Epidemiology Division, Research Triangle Institute International, Research Triangle Park, North Carolina, USA.
Kate BurdekinBiostatics and Epidemiology Division, Research Triangle Institute International, Research Triangle Park, North Carolina, USA.
Kevin CummiskeyDepartment of Mathematical Sciences, United States Military Academy, West Point, New York, USA.
Susan C J SumnerDepartment of Nutrition, Nutrition Research Institute, University of North Carolina Chapel Hill, Kannapolis, North Carolina, USA.
Wimal PathmasiriDepartment of Nutrition, Nutrition Research Institute, University of North Carolina Chapel Hill, Kannapolis, North Carolina, USA.
Edward SazonovElectrical and Computer Engineering Department, The University of Alabama, Tuscaloosa, Alabama, USA.
Kelley Pettee GabrielDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Erin E DooleyDepartment of Epidemiology, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Mark A GreenDepartment of Geography & Planning, University of Liverpool, Liverpool, UK.ORCID 0000-0002-0942-6628
Andrew PflugerDepartment of Geography and Environmental Engineering, United States Military Academy, West Point, New York, USA.
Samantha KleinbergComputer Science Department, Stevens Institute of Technology, Hoboken, New Jersey, USA.

Funding

Nutrition for Precision Health, powered by the All of Us Research Program: Research Coordinating CenterU24HD107676 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI MARIE G GANTZ, Saurabh Mehta · 2022 to 2026
$35.4M
UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Venkata Saroja Voruganti · 1999 to 2026
$31.6M
The UCSD Microbiome and Metagenomics Center (Summit Supplement)U24DK131617 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jack Anthony Gilbert, ROB KNIGHT · 2022 to 2026
$15.3M
Year 2, Targeted and Clinical Assay Supplement to the NPH MCACU24CA268153 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUMNER, SUSAN J · 2022 to 2025
$14.7M
UAB Precision Nutrition Clinical CenterUG1HD107688 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER, James O Hill · 2022 to 2026
$13.1M
Traditional and New Dietary Assessment Methods (TANDAM) for Personalized NutritionU24CA268228 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI EDWARD J DELP, MEGAN A MCCRORY · 2022 to 2026
$10.2M
Project 4: Virtual Public Health Precision Nutrition LaboratoryU54TR004279 · NCATS · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI Bruce Y Lee · 2022 to 2026
$5.4M
Artificial Intelligence and Precision Nutrition Training ProgramT32HD113301 · NICHD · CORNELL UNIVERSITY · PI David Carl Erickson, Deborah Estrin · 2023 to 2026
$1.1M
NCATS NIH HHS U54 TR004279NCI NIH HHS U24 CA268153NCI NIH HHS U24 CA268228NICHD NIH HHS T32 HD113301NICHD NIH HHS U24 HD107676NICHD NIH HHS UG1 HD107688NIDDK NIH HHS P30 DK056350NIDDK NIH HHS U24 DK131617NIH HHS 1U24DK131617-01NIH HHS U24CA268153NIH HHS U54TR004279NIH HHS UG1HD107688US Department of Defense EW22-7278
6 · The paper itself

Abstract

objectiveBig Data are increasingly used in obesity and nutrition research to gain new insights and derive personalized guidance; however, this data in raw form are often not usable. Substantial preprocessing, which requires machine learning (ML), human judgment, and specialized software, is required to transform Big Data into artificial intelligence (AI)- and ML-ready data. These preprocessing steps are the most complex part of the entire modeling pipeline. Understanding the complexity of these steps by the end user is critical for reducing misunderstanding, faulty interpretation, and erroneous downstream conclusions.

methodsWe reviewed three popular obesity/nutrition Big Data sources: microbiome, metabolomics, and accelerometry. The preprocessing pipelines, specialized software, challenges, and how decisions impact final AI- and ML-ready products were detailed.

resultsOpportunities for advances to improve quality control, speed of preprocessing, and intelligent end user consumption were presented.

conclusionsBig Data have the exciting potential for identifying new modifiable factors that impact obesity research. However, to ensure accurate interpretation of conclusions arising from Big Data, the choices involved in preparing AI- and ML-ready data need to be transparent to investigators and clinicians relying on the conclusions.

Indexed as

Artificial IntelligenceBig DataNutritional SciencesObesityAccelerometryBiomedical ResearchHumansMachine LearningMetabolomicsSoftware

Identifiers

PMID38426232
PMCPMC11180473

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.