Evidence map›Paper›PMID 38426054›Full record

ArticleFrontiers in microbiology2024

Interactions and effects of a stannous-containing sodium fluoride dentifrice on oral pathogens and the oral microbiome.

Danyan Chen, Dillon Chew, Qianfeng Xiang, TzeHau Lam, Yajie Dai, Jiquan Liu, Lijiang Wang, Tao He, Ross Strand, Xiaolan Zhang and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Danyan ChenState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Dillon ChewSingapore Innovation Center, The Procter & Gamble Company, Singapore, Singapore.
Qianfeng XiangDepartment of Dentistry-Regenerative Biomaterials, Radboud University Medical Center, Nijmegen, Netherlands.
TzeHau LamSingapore Innovation Center, The Procter & Gamble Company, Singapore, Singapore.
Yajie DaiSingle-Cell Center, CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Shandong Energy Institute, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China.
Jiquan LiuSingapore Innovation Center, The Procter & Gamble Company, Singapore, Singapore.
Lijiang WangProcter & Gamble Technology Co. Ltd, Beijing, China.
Tao HeThe Procter & Gamble Company, Mason, OH, United States.
Ross StrandSingapore Innovation Center, The Procter & Gamble Company, Singapore, Singapore.
Xiaolan ZhangInstitute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Linda LimSingapore Innovation Center, The Procter & Gamble Company, Singapore, Singapore.
Jian XuSingle-Cell Center, CAS Key Laboratory of Biofuels and Shandong Key Laboratory of Energy Genetics, Shandong Energy Institute, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong, China.
Yunming ShiProcter & Gamble Technology Co. Ltd, Beijing, China.
Weili DongState Key Laboratory of Oral and Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Qingdao Institute of Bioenergy and Bioprocess Technology · CNWuhan University · CNChinese Academy of Sciences · CNProcter & Gamble (United States) · USRadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Numerous studies have investigated the effects of stannous ions on specific microbes and their efficacy in reducing dental plaque. Nonetheless, our understanding of their impact on the oral microbiome is still a subject of ongoing exploration. Therefore, this study sought to evaluate the effects of a stannous-containing sodium fluoride dentifrice in comparison to a zinc-containing sodium fluoride dentifrice and a control group on intact, healthy oral biofilms. Utilizing the novel 2bRAD-M approach for species-resolved metagenomics, and FISH/CLSM with probes targeting periodontal and caries associated species alongside Sn

Indexed as

2bRAD-Mconfocal laser scanning microscopy (CLSM)fluorescence in situ hybridization (FISH)in situ biofilmoral microbiomestannous-containing dentifrice

Identifiers

PMID38426054
PMCPMC10902866
OpenAlexW4391837020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.