Evidence map›Paper›PMID 38425924›Full record

ArticleJACS Au2024

Dual Functionality of 6-Methylthioguanine: Synergistic Effects Enhancing the Photolability of DNA Nucleobases.

Qian Zhou, Yuxia Hao, Jialong Jie, Shuo Wang, Ye Xia, Chunfan Yang, Lihong Liu, Wei-Hai Fang, Hongmei Su

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JACS Au, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Qian ZhouCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Yuxia HaoCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Jialong JieCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Shuo WangCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Ye XiaCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Chunfan YangCollege of Chemistry, Beijing Normal University, Beijing 100875, China.
Lihong LiuCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID https://orcid.org/0000-0003-3063-6184
Wei-Hai FangCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID https://orcid.org/0000-0002-1668-465X
Hongmei SuCollege of Chemistry, Beijing Normal University, Beijing 100875, China.ORCID https://orcid.org/0000-0001-7384-6523
Beijing Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A small chemical modification of the nucleobase structure can significantly enhance the photoactivity of DNA, which may incur DNA damage, thus holding promising applications in photochemotherapy treatment of cancers or pathogens. However, single substitution confers only limited phototoxicity to DNA. Herein, we combine femtosecond and nanosecond time-resolved spectroscopy with high-level

Identifiers

PMID38425924
PMCPMC10900203
OpenAlexW4391145570

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.