Evidence map›Paper›PMID 38425692›Full record

ArticleClinical and translational radiation oncology2024

Comparison of conventional and hippocampus-sparing radiotherapy in nasopharyngeal carcinoma: In silico study and systematic review.

Monika Peternel, Aljaša Jenko, Primož Peterlin, Larisa Petrovič, Primož Strojan, Gaber Plavc

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational radiation oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Monika PeternelInstitute of Oncology, Department of Radiotherapy, Zaloška cesta 2, Ljubljana, Slovenia.
Aljaša JenkoInstitute of Oncology, Department of Radiotherapy, Zaloška cesta 2, Ljubljana, Slovenia.
Primož PeterlinInstitute of Oncology, Department of Radiotherapy, Zaloška cesta 2, Ljubljana, Slovenia.
Larisa PetrovičInstitute of Oncology, Department of Radiotherapy, Zaloška cesta 2, Ljubljana, Slovenia.
Primož StrojanInstitute of Oncology, Department of Radiotherapy, Zaloška cesta 2, Ljubljana, Slovenia.
Gaber PlavcInstitute of Oncology, Department of Radiotherapy, Zaloška cesta 2, Ljubljana, Slovenia.
Institute of Oncology Ljubljana · SIUniversity of Ljubljana · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and purpose: Radiation-induced damage to the hippocampi can cause cognitive decline. International recommendations for nasopharyngeal cancer (NPC) radiotherapy (RT) lack specific guidelines for protecting the hippocampi. Our study evaluates if hippocampi-sparing (HS) RT in NPC ensures target coverage and meets recommended dose limits for other at-risk organs. Materials and methods: In a systematic literature review, we compared hippocampal D Results: In four previous studies (n = 79), researchers reduced D Conclusion: Sparing the hippocampus in NPC RT is safe and feasible. Given the life expectancy of many NPC patients, their cognitive well-being must be paramount in radiotherapy planning.

Indexed as

Cognitive declineHippocampiNasopharyngeal cancerRadiation-induced damageRadiotherapy

Identifiers

PMID38425692
PMCPMC10900111
OpenAlexW4391942862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.