Evidence map›Paper›PMID 38425055›Full record

ArticleRenal failure2024

Disparity of serum uric acid threshold for CKD among hypertensive and non-hypertensive individuals.

Bowen Zhu, Fang Li, Weidong Zhang, Shuan Zhao, Nana Song, Shi Jin, Ziyan Shen, Yufei Lu, Yang Li, Hong Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bowen ZhuDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Fang LiDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Weidong ZhangDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Shuan ZhaoDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Nana SongDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Shi JinDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ziyan ShenDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yufei LuDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Yang LiDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.
Hong LiuDepartment of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHypertension and rising serum uric acid (sUA) played a pivotal role in the development of Chronic Kidney Disease (CKD). This study investigates the interactive effect of sUA and hypertension on CKD and identifies the optimal threshold of sUA among individuals with and without hypertension in the Chinese community population. MATERIALS AND

methodsThe study included 4180 individuals aged 45-85 years, derived from the China Health and Retirement Longitudinal Study (CHARLS) between 2011 and 2015. Additionally, a hospital-based study enrolled subjects in the Department of Nephrology at Zhongshan Hospital, China from January 1, 2019, to December 31, 2021. The interaction effect analysis were used to assess the impact of sUA and hypertension on CKD. We also compared the distribution of sUA and the CKD risk in community populations, distinguishing between those with and without hypertension. For the hospital-based population, kidney injury was marked by a KIM-1 positive area.

resultsOur results indicate a higher prevalence of CKD in the community population with hypertension (10.2% vs. 3.9%,

conclusionTherefore, even moderate levels of sUA was associated with a higher risk of CKD in middle-aged hypertensive patients, who warrant stricter sUA control.

Indexed as

HypertensionRenal Insufficiency, ChronicCross-Sectional StudiesHumansLongitudinal StudiesMiddle AgedRisk FactorsUric AcidUric AcidCHARLSchronic kidney diseaseHypertensionserum uric acid

Identifiers

PMID38425055
PMCPMC10911134

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.