Evidence map›Paper›PMID 38424728›Full record

ArticleDrug delivery2024

Photo-crosslinkable polyester microneedles as sustained drug release systems toward hypertrophic scar treatment.

Anna Szabó, Ignace De Decker, Sam Semey, Karel E Y Claes, Phillip Blondeel, Stan Monstrey, Jo Van Dorpe, Sandra Van Vlierberghe

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Anna SzabóPolymer Chemistry and Biomaterials Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium.
Ignace De DeckerBurn Center, Ghent University Hospital, Ghent, Belgium.
Sam SemeyPolymer Chemistry and Biomaterials Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium.
Karel E Y ClaesBurn Center, Ghent University Hospital, Ghent, Belgium.
Phillip BlondeelBurn Center, Ghent University Hospital, Ghent, Belgium.
Stan MonstreyBurn Center, Ghent University Hospital, Ghent, Belgium.
Jo Van DorpeDepartment of Pathology, Ghent University Hospital, Ghent, Belgium.
Sandra Van VlierberghePolymer Chemistry and Biomaterials Group, Centre of Macromolecular Chemistry (CMaC), Department of Organic and Macromolecular Chemistry, Ghent University, Ghent, Belgium.
Ghent University Hospital · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn injuries can result in a significant inflammatory response, often leading to hypertrophic scarring (HTS). Local drug therapies e.g. corticoid injections are advised to treat HTS, although they are invasive, operator-dependent, extremely painful and do not permit extended drug release. Polymer-based microneedle (MN) arrays can offer a viable alternative to standard care, while allowing for direct, painless dermal drug delivery with tailorable drug release profile. In the current study, we synthesized photo-crosslinkable, acrylate-endcapped urethane-based poly(

Indexed as

Cicatrix, HypertrophicPolyestersAdministration, CutaneousDrug Delivery SystemsDrug LiberationHumansNeedlesPharmaceutical PreparationsPolymersSkinPharmaceutical PreparationsPolyestersPolymerscontrolled drug releasecortisonehypertrophic scarringintradermal drug deliveryMicroneedlespolyester

Identifiers

PMID38424728
PMCPMC10956933
OpenAlexW4392353545

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.