Evidence map›Paper›PMID 38424520›Full record

ArticleBMC pediatrics2024

The response of CD27

Yunying Zhu, Qian Jiang, Chenshuang Lei, Qinhua Yu, Liannv Qiu

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Yunying Zhu *Laboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital),Hangzhou Medical College, Hangzhou, 310014, China.
Qian Jiang *Department of Clinical Laboratory, Ningbo Puji Hospital (Ningbo Second Hospital West Hospital), Ningbo, 315099, Zhejiang, China.
Chenshuang LeiDepartment of Clinical Laboratory, Wenzhou Central Hospital, Wenzhou, 325099, China.
Qinhua YuLaboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital),Hangzhou Medical College, Hangzhou, 310014, China.
Liannv QiuLaboratory Medicine Center, Department of Clinical Laboratory, Zhejiang Provincial People's Hospital(Affiliated People's Hospital),Hangzhou Medical College, Hangzhou, 310014, China. qlv2012@126.com.
Zhejiang Provincial People's Hospital · CNNingbo No. 2 Hospital · CNWenzhou Central Hospital · CNZhejiang Chinese Medical University · CN

Funding

the Natural Science Foundation of Zhejiang Province Y18H200014
6 · The paper itself

Abstract

backgroundAllergic asthma is a type I allergic reaction mediated by serum Immunoglobulin E (IgE). B cell-mediated humoral immune response to allergens in the pathophysiology of allergic asthma have not been thoroughly elucidated. Peripheral helper T cells (Tph) and follicular helper T cells (Tfh) promote B cell differentiation and antibody production in inflamed tissues.

objectiveTo investigate the roles of B cell subsets, Tph cell subsets and Tfh cell subsets in allergic immune responses.

methodsCirculating B cell subsets, Tph cell subsets and Tfh cell subsets in 33 children with allergic asthma and 17 healthy children were analyzed using multicolor flow cytometry. The level of serum total IgE was also assessed.

resultsOur study found that CD27

conclusionOverall, these results provide insight into the allergens elicited B, Tph or Tfh cell response and identify heretofore unappreciated CD24

Indexed as

AsthmaProgrammed Cell Death 1 ReceptorAllergensCD24 AntigenChildHumansImmunoglobulin EInducible T-Cell Co-Stimulator ProteinPrecursor Cells, B-LymphoidReceptors, CXCR5AllergensCD24 AntigenCD24 protein, humanCXCR5 protein, humanICOS protein, humanImmunoglobulin EInducible T-Cell Co-Stimulator ProteinProgrammed Cell Death 1 ReceptorReceptors, CXCR5Allergic asthmaB cell subsetsFlow cytometryIgEPeripheral helper T cell

Identifiers

PMID38424520
PMCPMC10902953
OpenAlexW4392295702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.