Evidence map›Paper›PMID 38424481›Full record

SynthesisBMC pregnancy and childbirth2024

Hygiene-based measures for the prevention of cytomegalovirus infection in pregnant women: a systematic review.

María F Rodríguez-Muñoz, Clara Martín-Martín, Katina Kovacheva, Maria Eugenia Olivares, Nuria Izquierdo, Pilar Pérez-Romero, Estéfani García-Ríos

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC pregnancy and childbirth, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

María F Rodríguez-MuñozFaculty of Psychology, Universidad Nacional de Educación a Distancia, (UNED), Madrid, Spain.
Clara Martín-MartínNational Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Carretera Majadahonda - Pozuelo km. 2, Majadahonda, Madrid, 28220, Spain.
Katina KovachevaFaculty of Psychology, Universidad Nacional de Educación a Distancia, (UNED), Madrid, Spain.
Maria Eugenia OlivaresDepartment of Gynecology and Obstetrics, Hospital Clínico San Carlos, Madrid, Spain.
Nuria IzquierdoDepartment of Gynecology and Obstetrics, Hospital Clínico San Carlos, Madrid, Spain.
Pilar Pérez-RomeroDepartment of Biological Sciences, University of Notre Dame, Notre Dame, IN, 46556, USA.
Estéfani García-RíosNational Centre for Microbiology, Instituto de Salud Carlos III (ISCIII), Carretera Majadahonda - Pozuelo km. 2, Majadahonda, Madrid, 28220, Spain. e.garcia.rios@iata.csic.es.
Hospital Clínico San Carlos · ESNational University of Distance Education · ESInstituto de Agroquímica y Tecnología de Alimentos · ESInstituto de Salud Carlos III · ESUniversity of Notre Dame · US

Funding

Conselleria de Cultura, Educación y Ciencia, Generalitat Valenciana CIDEIG/2022/28Instituto de Salud Carlos III CD18CIII/00007Instituto de Salud Carlos III FI22CIII/0029Universidad Nacional de Educación a Distancia Proyectos de Iniciación a la Investigación 2022
6 · The paper itself

Abstract

backgroundHuman Cytomegalovirus (HCMV) is the most frequent congenital infection worldwide causing important sequelae. However, no vaccine or antiviral treatments are currently available, thus interventions are restricted to behavioral measures. The aim of this systematic review was to assess evidence from available intervention studies using hygiene-based measures to prevent HCMV infection during pregnancy.

methodsStudies published from 1972 to 2023 were searched in Medline, PsycInfo, and Clinical Trials (PROSPERO, CRD42022344840) according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Methodological quality was assessed by two authors, using ROBE-2 and MINORS.

resultsAfter reviewing 6 selected articles, the outcome analysis suggested that implementation of hygiene-based interventions during pregnancy prevent, to some extent, the acquisition of congenital HCMV.

conclusionsHowever, these conclusions are based on limited and low-quality evidence available from few studies using this type of intervention in clinical practice. Thus, it would be necessary to perform effective and homogeneous intervention studies using hygiene-based measures, evaluated in high-quality randomized controlled trials (RCTs).

Indexed as

Cytomegalovirus InfectionsPregnancy Complications, InfectiousCytomegalovirusFemaleHumansHygienePregnancyCounsellingCytomegalovirusPregnancySeroconversionSystematic review

Identifiers

PMID38424481
PMCPMC10905865
OpenAlexW4392298314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.