Evidence map›Paper›PMID 38424411›Full record

ArticleIntensive care medicine experimental2024

Development of personalized non-invasive ventilation masks for critically ill children: a bench study.

Rosemijne R W P Pigmans, Rozalinde Klein-Blommert, Monica C van Gestel, Dick G Markhorst, Peter Hammond, Pim Boomsma, Tim Daams, Julia M A de Jong, Paul M Heeman, Job B M van Woensel and 2 more

Open access · goldAbstract read
In one paragraph

Article in Intensive care medicine experimental, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Rosemijne R W P PigmansPediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. r.r.pigmans@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-3939-4169
Rozalinde Klein-BlommertPediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Monica C van GestelPediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Dick G MarkhorstPediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Peter HammondNuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Pim BoomsmaDepartment for Medical Innovation and Development, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Tim DaamsDepartment for Medical Innovation and Development, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Julia M A de JongDepartment for Medical Innovation and Development, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Paul M HeemanDepartment for Medical Innovation and Development, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Job B M van WoenselPediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Coen D DijkmanDepartment for Medical Innovation and Development, Amsterdam University Medical Centers, Amsterdam, The Netherlands.
Reinout A BemPediatric Intensive Care Unit, Emma Children's Hospital, Amsterdam UMC, Location AMC, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Amsterdam University Medical Centers · NLEmma Kinderziekenhuis · NLAmsterdam University of Applied Sciences · NLOpen Data Institute · GB

Funding

Cornelia Foundation CS 20210068Innovation Award Amsterdam UMC 2022-06
6 · The paper itself

Abstract

backgroundObtaining a properly fitting non-invasive ventilation (NIV) mask to treat acute respiratory failure is a major challenge, especially in young children and patients with craniofacial abnormalities. Personalization of NIV masks holds promise to improve pediatric NIV efficiency. As current customization methods are relatively time consuming, this study aimed to test the air leak and surface pressure performance of personalized oronasal face masks using 3D printed soft materials. Personalized masks of three different biocompatible materials (silicone and photopolymer resin) were developed and tested on three head models of young children with abnormal facial features during preclinical bench simulation of pediatric NIV. Air leak percentages and facial surface pressures were measured and compared for each mask.

resultsPersonalized NIV masks could be successfully produced in under 12 h in a semi-automated 3D production process. During NIV simulation, overall air leak performance and applied surface pressures were acceptable, with leak percentages under 30% and average surface pressure values mostly remaining under normal capillary pressure. There was a small advantage of the masks produced with soft photopolymer resin material.

conclusionThis first, proof-of-concept bench study simulating NIV in children with abnormal facial features, showed that it is possible to obtain biocompatible, personalized oronasal masks with acceptable air leak and facial surface pressure performance using a relatively short, and semi-automated production process. Further research into the clinical value and possibilities for application of personalized NIV masks in critically ill children is needed.

Indexed as

3D printingAcute respiratory failureCustomizationFace maskNon-invasive respiratory supportPediatric intensive care unit

Identifiers

PMID38424411
PMCPMC10904697
OpenAlexW4392767418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.