Evidence map›Paper›PMID 38424390›Full record

ArticleCanadian journal of anaesthesia = Journal canadien d'anesthesie2024

Association of chronic poststernotomy pain and health-related quality of life: a prospective cohort study.

Terri Sun, Mikayla Fan, Defen Peng, Lauren Li, Alyson Ree, Alana M Flexman, Ainsley M Sutherland, Stephan K W Schwarz, Tim Ting Han Jen, Cynthia H Yarnold

Open access · bronzeAbstract read
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In one paragraph

Article in Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Anemia after cardiac surgery: what is its link to outcomes?Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Terri SunDepartment of Anesthesia, St. Paul's Hospital/Providence Health Care, Level 3 Providence Building, 1081 Burrard St., Vancouver, BC, V6Z 1Y6, Canada. terri.sun@gmail.com.ORCID 0000-0003-1937-3838
Mikayla FanDepartment of Anesthesia, St. Paul's Hospital/Providence Health Care, Vancouver, BC, Canada.
Defen PengCentre for Cardiovascular Innovation, The University of British Columbia, Vancouver, BC, Canada.
Lauren LiRoyal College of Surgeons in Ireland / University of Medicine and Health Sciences, Dublin, Ireland.
Alyson ReeFaculty of Medicine, McMaster University, Hamilton, ON, Canada.
Alana M FlexmanDepartment of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Ainsley M SutherlandDepartment of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Stephan K W SchwarzDepartment of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-3584-1032
Tim Ting Han JenDepartment of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-6999-0458
Cynthia H YarnoldDepartment of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.
Providence Health Care · CAMcMaster University · CARoyal College of Surgeons in Ireland · IEUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic poststernotomy pain (CPSP) after cardiac surgery is multifactorial and impacts patient recovery. We aimed to evaluate the association between CPSP severity and health-related quality of life at six months after cardiac surgery.

methodsThis was a single-centre prospective cohort study of patients who underwent cardiac surgery with median sternotomy between September 2020 and March 2021. Telephone interviews were conducted at six and 12 months postoperatively using the Short Form McGill Pain Questionnaire and the EQ-5D-5L. Strength of correlation was described using Spearman's correlation coefficient. Multivariable regression analysis was used to account for confounding variables.

resultsA total of 252 patients responded to the six-month interview (response rate, 65%). The mean (standard deviation) age of respondents was 65 (13) yr. Twenty-nine percent of respondents (72/252) reported CPSP at six months, and 14% (41/252) reported more than mild pain (score ≥ 2/5). At 12 months, of the 89% (64/72) patients who responded, 47% (30/64) still reported pain. The strength of the correlation between pain scores and EQ-5D-5L was weak (Spearman's correlation coefficient, -0.3). Risk factors for CPSP at six months included higher pain score on postoperative day 1, history of chronic pain prior to surgery, and history of depression. Intraoperative infusion of dexmedetomidine or ketamine was associated with a reduced risk of CPSP at six months.

conclusionChronic poststernotomy pain still affects patient recovery at six and 12 months after cardiac surgery. The severity of that pain is poorly correlated with patients' quality of life. STUDY REGISTRATION: www.osf.io ( https://osf.io/52rsw ); registered 14 May 2022.

Indexed as

Chronic PainHumansPostoperative PainProspective StudiesQuality of Lifecardiac surgerychronic sternotomy pain

Identifiers

PMID38424390
OpenAlexW4392281812

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.