Evidence map›Paper›PMID 38424208›Full record

ArticleScientific reports2024

Designing a T-cell epitope-based vaccine using in silico approaches against the Sal k 1 allergen of Salsola kali plant.

Mohammad Hossein Shams, Seyyed Mohsen Sohrabi, Reza Jafari, Ali Sheikhian, Hossein Motedayyen, Peyman Amanolahi Baharvand, Amin Hasanvand, Ali Fouladvand, Mohammad-Ali Assarehzadegan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Mohammad Hossein ShamsHepatitis Research Center and Department of Medical Immunology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran. hosseinshams62@yahoo.com.
Seyyed Mohsen SohrabiDepartment of Production Engineering and Plant Genetic, Faculty of Agriculture, Shahid Chamran University of Ahvaz, Box 6814993165, Ahvaz, Iran.
Reza JafariSchool of Allied Medical Sciences, Shahroud University of Medical Sciences, Shahroud, Iran.
Ali SheikhianHepatitis Research Center and Department of Medical Immunology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Hossein MotedayyenAutoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran.
Peyman Amanolahi BaharvandHepatitis Research Center and Department of Medical Immunology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Amin HasanvandDepartment of Physiology and Pharmacology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Ali FouladvandHepatitis Research Center and Department of Medical Immunology, School of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran.
Mohammad-Ali AssarehzadeganImmunology Research Center, Department of Immunology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. assarehma@gmail.com.
Lorestan University of Medical Sciences · IRIran University of Medical Sciences · IRKashan University of Medical Sciences · IRShahid Chamran University of Ahvaz · IRShahroud University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergens originated from Salsola kali (Russian thistle) pollen grains are one of the most important sources of aeroallergens causing pollinosis in desert and semi-desert regions. T-cell epitope-based vaccines (TEV) are more effective among different therapeutic approaches developed to alleviate allergic diseases. The physicochemical properties, and B as well as T cell epitopes of Sal k 1 (a major allergen of S. kali) were predicted using immunoinformatic tools. A TEV was constructed using the linkers EAAAK, GPGPG and the most suitable CD4

Indexed as

ChenopodiaceaeSalsolaVaccinesAllergensAntigens, PlantComputational BiologyEpitopes, B-LymphocyteEpitopes, T-LymphocyteHumansMolecular Docking SimulationToll-Like Receptor 4Vaccines, SubunitAllergensAntigens, PlantEpitopes, B-LymphocyteEpitopes, T-LymphocyteToll-Like Receptor 4VaccinesVaccines, SubunitAllergen-specific immunotherapyImmunoinformaticsIn silicoSal k 1Salsola kaliT-cell epitope-based vaccineVaccine

Identifiers

PMID38424208
PMCPMC10904830
OpenAlexW4392282663

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.